Evidence map›Paper›PMID 26598947›Full record

ReviewNature reviews. Clinical oncology2016

Integrating palliative care into the trajectory of cancer care.

David Hui, Eduardo Bruera

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature reviews. Clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02724683 (Management of Symptomatic Malignant Ascites With an Patient-controlled, Vascular Catheter - a Validation Study.), which is not on this map. Cited by 182 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed, 9 pooled it
33.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02724683 unknown statusnot on this map

Management of Symptomatic Malignant Ascites With an Patient-controlled, Vascular Catheter - a Validation Study.

Typeobservational_patient_registrySponsorMaciej Stukan, MD, PhDRan2016 to 2023Enrolled170ConditionsMalignant AscitesArmsAscites drainage with vascular catheter., Interview., Quality of life., Quality of procedure., Nutritional status
3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 9 syntheses or guidelines pooled it, 405 citations in OpenAlex.

  1. Pooled it
  2. Application of virtual reality for supportive care in cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Palliative Oncologic Care Curricula for Providers in Resource-Limited and Underserved Communities: a Systematic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2019
    Pooled it
  9. Pooled it
  10. Proactive symptom monitoring to initiate timely palliative care for patients with advanced cancer: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  11. Trial
  12. The impact of early palliative care on the quality of life of patients with advanced pancreatic cancer: The IMPERATIVE case-crossover study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  13. Application of interdisciplinary collaborative hospice care for terminal geriatric cancer patients: a prospective randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  14. Trial
  15. Trial
  16. Systematic vs. on-demand early palliative care in gastric cancer patients: a randomized clinical trial assessing patient and healthcare service outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
  17. Trial
  18. Role of Patient Coping Strategies in Understanding the Effects of Early Palliative Care on Quality of Life and Mood.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Trial
  19. Effects of Early Integrated Palliative Care in Patients With Lung and GI Cancer: A Randomized Clinical Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
    Trial
  20. Trial

122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David HuiDepartment of Palliative Care &Rehabilitation Medicine, Unit 1414, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.
Eduardo BrueraDepartment of Palliative Care &Rehabilitation Medicine, Unit 1414, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.
The University of Texas MD Anderson Cancer Center · US

Funding

Parenteral Hydration in Advanced Cancer Patients: A Randomized Controlled TrialR01CA122292 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BRUERA, EDUARDO · 2006 to 2009
$2.2M
Methylphenidate for Fatigue in Advanced Cancer PatientsR01NR010162 · NINR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BRUERA, EDUARDO · 2006 to 2009
$1.3M
Morphine versus Methadone as First Line Strong Opioid for Cancer PainR01CA124481 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BRUERA, EDUARDO · 2007 to 2009
$1.2M
Adjuvant Lorazepam for Agitated Delirium in the Palliative Care UnitR21CA186000 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2015 to 2016
$399k
NCI NIH HHS R01 CA122292NCI NIH HHS R01CA122292‑01NCI NIH HHS R01 CA124481NCI NIH HHS R01CA124481‑01NCI NIH HHS R21 CA186000NCI NIH HHS R21CA186000‑01A1NINR NIH HHS R01 NR010162NINR NIH HHS R01NR010162‑01A1
6 · The paper itself

Abstract

Over the past five decades, palliative care has evolved from serving patients at the end of life into a highly specialized discipline focused on delivering supportive care to patients with life-limiting illnesses throughout the disease trajectory. A growing body of evidence is now available to inform the key domains in the practice of palliative care, including symptom management, psychosocial care, communication, decision-making, and end-of-life care. Findings from multiple studies indicate that integrating palliative care early in the disease trajectory can result in improvements in quality of life, symptom control, patient and caregiver satisfaction, illness understanding, quality of end-of-life care, survival, and costs of care. In this narrative Review, we discuss various strategies to integrate oncology and palliative care by optimizing clinical infrastructures, processes, education, and research. The goal of integration is to maximize patient access to palliative care and, ultimately, to improve patient outcomes. We provide a conceptual model for the integration of supportive and/or palliative care with primary and oncological care. We also discuss how health-care systems and institutions need to tailor integration based on their resources, size, and the level of primary palliative care available.

Indexed as

Combined Modality TherapyCritical PathwaysDelivery of Health Care, IntegratedHealth Services AccessibilityHumansModels, OrganizationalNeoplasmsOrganizational InnovationPalliative CarePatient Care TeamPatient-Centered CareQuality of LifeTreatment Outcome

Identifiers

PMID26598947
PMCPMC4772864
OpenAlexW2187153308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.