Evidence map›Paper›PMID 26598716›Full record

SynthesisBritish journal of sports medicine2016

Is there an association between tendinopathy and diabetes mellitus? A systematic review with meta-analysis.

Tom A Ranger, Andrea M Y Wong, Jill L Cook, Jamie E Gaida

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in British journal of sports medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 4 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 165 citations in OpenAlex.

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  9. An Angiotensin II Receptor Blocker Suppresses Glucose-Induced Oxidative Stress in Human Rotator Cuff-Derived Cells.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tom A RangerDepartment of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
Andrea M Y WongDepartment of Physiotherapy, Monash University, Melbourne, Victoria, Australia.
Jill L CookDepartment of Physiotherapy, Monash University, Melbourne, Victoria, Australia La Trobe University Sport and Exercise Medicine Research Centre, La Trobe University, Victoria, Australia.
Jamie E GaidaDepartment of Physiotherapy, Monash University, Melbourne, Victoria, Australia University of Canberra Research Institute for Sport and Exercise (UCRISE) Discipline of Physiotherapy, University of Canberra, Canberra, Australian Capital Territory, Australia.ORCID http://orcid.org/0000-0002-4504-9188
Monash University · AULa Trobe University · AUUniversity of Canberra · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMusculoskeletal symptoms limit adherence to exercise interventions for individuals with type 2 diabetes. People with diabetes may be susceptible to tendinopathy due to chronically elevated blood glucose levels. Therefore, we aimed to investigate this potential association by systematically reviewing and meta-analysing case-control, cross-sectional, and studies that considered both of these conditions.

methodsNine medical databases and hand searching methods were used without year limits to identify all relevant English language articles that considered diabetes and tendinopathy. Two authors applied exclusion criteria and one author extracted data with verification by a second author. Meta-analysis was conducted using a random effects model. Results were expressed as odds ratio (OR), mean difference or standardised mean difference with a confidence intervals (95% CI). Heterogeneity was assessed by I(2).

findings31 studies were included in the final analysis of which 26 recruited people with diabetes and five recruited people with tendinopathy. Tendinopathy was more prevalent in people with diabetes (17 studies, OR 3·67, 95% CI 2·71 to 4·97), diabetes was more prevalent in people with tendinopathy (5 studies, OR 1·28, 95% CI 1·10 to 1·49), people with diabetes and tendinopathy had a longer duration of diabetes than people with diabetes only (6 studies, mean difference 5·26 years, 95% CI 4·15 to 6·36) and people with diabetes had thicker tendons than controls (9 studies, standardised mean difference 0·79 95% CI 0·47 to 1·12).

interpretationThese findings provide strong evidence that diabetes is associated with higher risk of tendinopathy. This is clinically relevant as tendinopathy may affect adherence to exercise interventions for diabetes.

Indexed as

Case-Control StudiesCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2HumansMagnetic Resonance ImagingTendinopathyTomography, X-Ray ComputedDiabetes

Identifiers

PMID26598716
OpenAlexW2173199507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.