Evidence map›Paper›PMID 26598504›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2017

Proceedings of the 2015 ASPEN Research Workshop-Taste Signaling.

Alan C Spector, Carel W le Roux, Steven D Munger, Susan P Travers, Anthony Sclafani, Julie A Mennella

Open access · greenAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. MicroRNA-21 is a potential therapeutic agent targetingMolecular therapy. Nucleic acids · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Do Food Preferences Change After Bariatric Surgery?Current atherosclerosis reports · 2017
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Alan C Spector1 Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida, USA.
Carel W le Roux2 Diabetes Complications Research Centre, Conway Institute, University College, Dublin, Ireland.
Steven D Munger3 Department of Pharmacology and Therapeutics; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism; Center for Smell and Taste, University of Florida, Gainesville, Florida, USA.
Susan P Travers4 Division of Biosciences, College of Dentistry, Ohio State University, Columbus, Ohio, USA.
Anthony Sclafani5 Department of Psychology, Brooklyn College of the City University of New York, New York, New York, USA.
Julie A Mennella6 Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Brooklyn College · USFlorida State University · USMonell Chemical Senses Center · USThe Ohio State University · USUniversity College Dublin · IEUniversity of Florida · US

Funding

Taste of medicines for children: genetic variation and medical adherenceR01DC011287 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI LOWENTHAL, ELIZABETH DAWN, MENNELLA, JULIA ANNE · 2011 to 2022
$4.3M
MODEL FOR SENSITIVE PERIODS IN EARLY FLAVOR LEARNINGR01HD037119 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE · 1999 to 2016
$3.9M
GUSTATORY AFFERENT ORGANIZATION IN THE SOLITARY NUCLEUSR01DC000416 · NIDCD · OHIO STATE UNIVERSITY · PI TRAVERS, SUSAN P · 1992 to 2013
$2.7M
Impact of diet composition during infancy on energy balance, satiety and growthR01HD072307 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE, TRABULSI, JILLIAN CHRISTINE · 2012 to 2016
$2.7M
CARBOHYDRATE APPETITE, FAT APPETITE, AND OBESITYR01DK031135 · NIDDK · BROOKLYN COLLEGE · PI ACKROFF, KAREN, SCLAFANI, ANTHONY · 1986 to 2015
$2.0M
Mechanisms of alimentary chemosensationR01DC010110 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI MUNGER, STEVEN D · 2009 to 2013
$1.5M
Functional Organization of the Central Gustatory SystemR01DC009821 · NIDCD · FLORIDA STATE UNIVERSITY · PI SPECTOR, ALAN C · 2010 to 2014
$1.5M
Catecholaminergic Modulation of Taste Circuitry Using OptogeneticsR21DC013676 · NIDCD · OHIO STATE UNIVERSITY · PI TRAVERS, JOSEPH B · 2014 to 2015
$422k
Motivational Changes for Nutritionally Relevant Tastes after Gastric BypassR21DC012751 · NIDCD · FLORIDA STATE UNIVERSITY · PI SPECTOR, ALAN C · 2012 to 2013
$389k
A.S.P.E.N. 2015 RW Taste Signaling: Impact on Food Selection, Intake, and HealthR13DK102191 · NIDDK · AMERICAN SOCIETY/PARENT & ENTERAL NUTRIT · PI EARTHMAN, CARRIE P · 2014 to 2014
$19k
NICHD NIH HHS R01 HD037119NICHD NIH HHS R01 HD072307NIDCD NIH HHS R01 DC000416NIDCD NIH HHS R01 DC009821NIDCD NIH HHS R01 DC010110NIDCD NIH HHS R01 DC011287NIDCD NIH HHS R21 DC012751NIDCD NIH HHS R21 DC013676NIDDK NIH HHS R01 DK031135NIDDK NIH HHS R13 DK102191
6 · The paper itself

Abstract

This article summarizes research findings from 6 experts in the field of taste and feeding that were presented at the 2015 American Society for Parenteral and Enteral Nutrition Research Workshop. The theme was focused on the interaction of taste signals with those of a postingestive origin and how this contributes to regulation of food intake through both physiological and learning processes. Gastric bypass results in exceptional loss of fat mass and increases in circulating levels of key gut peptides, some of which are also expressed along with their cognate receptors in taste buds. Changes in taste preference and food selection in both bariatric surgery patients and rodent models have been reported. Accordingly, the effects of this surgery on taste-related behavior were examined. The conservation of receptor and peptide signaling mechanisms in gustatory and extraoral tissues was discussed in the context of taste responsiveness and the regulation of metabolism. New findings detailing the features of neural circuits between the caudal nucleus of the solitary tract (NST), receiving visceral input from the vagus nerve, and the rostral NST, receiving taste input, were discussed, as was how early life experience with taste stimuli and learned associations between flavor and postoral consequences of nutrients can exert potent and long-lasting effects on feeding.

Indexed as

AnimalsBariatric SurgeryBlood GlucoseCongresses as TopicDisease Models, AnimalFood PreferencesGastrointestinal HormonesHumansRatsReceptors, G-Protein-CoupledTasteTaste BudsBlood GlucoseGastrointestinal HormonesReceptors, G-Protein-Coupledproteinsresearch and diseasessurgery

Identifiers

PMID26598504
PMCPMC4877284
OpenAlexW2174143298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.