ArticleScientific reports2015
Source analysis of P3a and P3b components to investigate interaction of depression and anxiety in attentional systems.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Detecting electrophysiological alterations in psychiatric disorders through event-related microstates: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Hemispheric asymmetries and network dysfunctions in adolescent depression: A neuroimaging study using resting-state functional magnetic resonance imaging.World journal of psychiatry · 2025Trial
- Gender Differences and Comorbidities in Major Depression.Advances in experimental medicine and biology · 2026Review
- Investigation of functional connectivity differences based on anxiety tendencies.Frontiers in behavioral neuroscience · 2024Article
- Investigating mechanism of the effect of emotional facial expressions on attentional processing by data clustering approach.Scientific reports · 2023Article
- Attention bias modification for depression: A systematic review and meta-analysis.Frontiers in psychiatry · 2023Article
- Cortical Reorganization Following Psychoeducational Counselling and Residual Inhibition Therapy (RIT) in Individuals with Tinnitus.International archives of otorhinolaryngology · 2022Article
- Neural correlates of anxious distress in depression: A neuroimaging study of reactivity to emotional faces and resting-state functional connectivity.Depression and anxiety · 2022Article
- Article
- State anxiety influences P300 and P600 event-related potentials over parietal regions in the hollow-mask illusion experiment.Personality neuroscience · 2021Article
- The Prevalence of Depression, Anxiety and Stress and Their Associated Factors in College Students.International journal of environmental research and public health · 2020Article
- Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety.Translational psychiatry · 2020Article
- The Startle-Evoked Potential: Negative Affect and Severity of Pathology in Anxiety/Mood Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Effects of Transcutaneous Vagus Nerve Stimulation (tVNS) on the P300 and Alpha-Amylase Level: A Pilot Study.Frontiers in human neuroscience · 2018Article
- Motivated attention and family risk for depression: Neuronal generator patterns at scalp elicited by lateralized aversive pictures reveal blunted emotional responsivity.NeuroImage. Clinical · 2017Article
- Dynamic Responses in Brain Networks to Social Feedback: A Dual EEG Acquisition Study in Adolescent Couples.Frontiers in computational neuroscience · 2017Article
- Depression-Related Brain Connectivity Analyzed by EEG Event-Related Phase Synchrony Measure.Frontiers in human neuroscience · 2016Article
- Electroencephalographic Activity in Patients with Claustrophobia: A Pilot Study.Journal of medical signals and sensorsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined the impact of depressive disorders, anxiety disorders and the comorbidity of these disorders on the regional electrophysiological features of brain activity. Sixty-four-channel event-related potentials (ERP) were acquired during a visual oddball task in patients with depressive disorder, patients with anxiety disorders, patients with comorbid depressive and anxiety disorders and healthy subjects. An fMRI-constrained source model was applied to ERP to identify different cortical activities in the patient and control groups. Comorbid patients showed an abnormal frontal-greater-than-parietal P3b topography in the right hemisphere and the highest P3a amplitude at frontal and central sites at the scalp midline. For P3b, depressed patients showed decreased right-lateralized activity in the precentral sulcus (PrCS) and posterior parietal cortex (PPC). Anxious patients demonstrated hyperactive prefrontal cortices (PFC). Comorbid patients presented decreased activity in the cingulate gyrus, right PrCS and right PPC and increased activity in the left PFC and left insular (INS). For P3a, hyperactive left PrCS was found in comorbid patients. Comorbid patients showed both anxiety-related and depression-related activity. A superimposition effect of depression and anxiety was identified with (1) aggravated hypo-function of the right-lateralized dorsal attention and salience networks and (2) complicated anxiety-related hyper-function of the left-lateralized ventral attention and salience networks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.