Evidence map›Paper›PMID 26598018›Full record

ArticleLeukemia2016

Axl activates fibroblast growth factor receptor pathway to potentiate survival signals in B-cell chronic lymphocytic leukemia cells.

S Sinha, J Boysen, M Nelson, S L Warner, D Bearss, N E Kay, A K Ghosh

Abstract readLetter
In one paragraph

Article in Leukemia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. A Promising Paradigm Shift in Cancer Treatment with FGFR Inhibitors.Anti-cancer agents in medicinal chemistry · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S SinhaDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
J BoysenDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
M NelsonDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
S L WarnerTolero Pharmaceuticals, Inc., Salt Lake City, UT, USA.
D BearssTolero Pharmaceuticals, Inc., Salt Lake City, UT, USA.
N E KayDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
A K GhoshStephenson Cancer Center, Department of Pathology, The University of Oklahoma, Oklahoma City, OK, USA.
Mayo Clinic in Arizona · USTolero Pharmaceuticals (United States) · USUniversity of Oklahoma · US

Funding

Microvesicle Dynamics in B-Cell Chronic Lymphocytic Leukemia Tumor MicroenvironmeR01CA170006 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI GHOSH, ASISH KUMAR · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA170006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell SurvivalAxl Receptor Tyrosine KinaseCell Line, TumorFibroblast Growth FactorsHumansLeukemia, Lymphocytic, Chronic, B-CellPhosphorylationProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Fibroblast Growth FactorAXL protein, humanAxl Receptor Tyrosine KinaseFibroblast Growth FactorsProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Fibroblast Growth Factor

Identifiers

PMID26598018
PMCPMC4879100
OpenAlexW2175330263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.