ArticlePlant molecular biology2016
Telomere binding protein TRB1 is associated with promoters of translation machinery genes in vivo.
Article in Plant molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- Epigenetic gene regulation is controlled by distinct regulatory complexes utilizing specialized paralogs of TELOMERE REPEAT BINDING FACTORS.PLoS genetics · 2026Article
- TRB proteins in moss reveal their evolutionarily conserved roles in plant development and telomere maintenance.The Plant journal : for cell and molecular biology · 2025Article
- The leaves fall, yet the tree endures.Cellular and molecular life sciences : CMLS · 2025Review
- High resolution diel transcriptomes of autotetraploid potato reveal expression and sequence conservation among rhythmic genes.BMC genomics · 2025Article
- The TELOMERE REPEAT BINDING proteins TRB4 and TRB5 function as transcriptional activators of PRC2-controlled genes to regulate plant development.Plant communications · 2024Article
- Systematic characterization of photoperiodic gene expression patterns reveals diverse seasonal transcriptional systems in Arabidopsis.PLoS biology · 2023Article
- Completing the TRB family: newly characterized members show ancient evolutionary origins and distinct localization, yet similar interactions.Plant molecular biology · 2023Article
- Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14.Nature communications · 2023Article
- Cytokinins - regulators ofFrontiers in plant science · 2023Review
- Article
- Telomeres and Their Neighbors.Genes · 2022Review
- Article
- Review
- Buried in PEAT-discovery of a new silencing complex with opposing activities.The EMBO journal · 2018Article
- An armadillo-domain protein participates in a telomerase interaction network.Plant molecular biology · 2018Article
- Telobox motifs recruit CLF/SWN-PRC2 for H3K27me3 deposition via TRB factors in Arabidopsis.Nature genetics · 2018Article
- Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo.Protoplasma · 2017Article
- Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant Cell.Frontiers in plant science · 2016Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently we characterised TRB1, a protein from a single-myb-histone family, as a structural and functional component of telomeres in Arabidopsis thaliana. TRB proteins, besides their ability to bind specifically to telomeric DNA using their N-terminally positioned myb-like domain of the same type as in human shelterin proteins TRF1 or TRF2, also possess a histone-like domain which is involved in protein-protein interactions e.g., with POT1b. Here we set out to investigate the genome-wide localization pattern of TRB1 to reveal its preferential sites of binding to chromatin in vivo and its potential functional roles in the genome-wide context. Our results demonstrate that TRB1 is preferentially associated with promoter regions of genes involved in ribosome biogenesis, in addition to its roles at telomeres. This preference coincides with the frequent occurrence of telobox motifs in the upstream regions of genes in this category, but it is not restricted to the presence of a telobox. We conclude that TRB1 shows a specific genome-wide distribution pattern which suggests its role in regulation of genes involved in biogenesis of the translational machinery, in addition to its preferential telomeric localization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.