ArticleIranian biomedical journal2016
Association Study of rs1333040 and rs1004638 Polymorphisms in the 9p21 Locus with Coronary Artery Disease in Southwest of Iran.
Article in Iranian biomedical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Prognostic value ofInternational journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Association between rs3088440 (G > A) polymorphism at 9p21.3 locus with the occurrence and severity of coronary artery disease in an Iranian population.Molecular biology reports · 2021Article
- The Emerging Role of Long Non-coding RNAs and Circular RNAs in Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Review
- Association of single-nucleotide polymorphism on chromosome 9 and ischemic stroke in Heilongjiang province in China.International journal of clinical and experimental pathology · 2021Article
- The association between the chromosome 9p21 CDKN2B-AS1 gene variants and the lipid metabolism: A pre-diagnostic biomarker for coronary artery disease.Anatolian journal of cardiology · 2019Article
- Association of rs1333040 SNPs with susceptibility, risk factors, and clinical characteristics of acute myocardial infarction patients in a Chinese Han population.International journal of clinical and experimental pathology · 2018Article
- CDKN2BAS polymorphisms are associated with coronary heart disease risk a Han Chinese population.Oncotarget · 2016Article
- Chromosome 9p21 and ABCA1 Genetic Variants and Their Interactions on Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population.International journal of molecular sciences · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronary artery disease (CAD) is a multifactorial and heterogenic disease. Recently, genome-wide association studies have reported that rs1333040 (C/T) and rs1004638 (A/T) single nucleotide polymorphisms (SNPs) in the 9p21 locus have very strong association with CAD. This study aimed to examine these associations in Southwest of Iran.
methodsBlood samples were collected from 200 CAD patients and 110 healthy individuals with no CAD. The association of two SNPs with CAD was evaluated by PCR and restriction fragment length polymorphism.
resultsChi-square test showed no association between rs1333040 SNP and CAD (X2: 4.66, df: 2, P=0.09). Also, there was no association between rs1004638 SNP and CAD (X2: 0.27, df: 2, P=0.88).
conclusionNo association was observed between rs1333040 and rs1004638 SNPs in the 9P21 region and CAD in Southwest of Iran.
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