Evidence map›Paper›PMID 26596940›Full record

ArticleAntimicrobial agents and chemotherapy2016

Activity of Fosfomycin against Extended-Spectrum-β-Lactamase-Producing Uropathogens in Patients in the Community and Hospitalized Patients.

Katherine Linsenmeyer, Judith Strymish, Susan Weir, Gretchen Berg, Stephen Brecher, Kalpana Gupta

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Katherine LinsenmeyerVA Boston Healthcare System, West Roxbury, Massachusetts, USA Boston University School of Medicine, Boston, Massachusetts, USA katherine.linsenmeyer@bmc.org.
Judith StrymishVA Boston Healthcare System, West Roxbury, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA.
Susan WeirVA Boston Healthcare System, West Roxbury, Massachusetts, USA Boston University School of Medicine, Boston, Massachusetts, USA.
Gretchen BergVA Boston Healthcare System, West Roxbury, Massachusetts, USA Boston University School of Medicine, Boston, Massachusetts, USA.
Stephen BrecherVA Boston Healthcare System, West Roxbury, Massachusetts, USA Boston University School of Medicine, Boston, Massachusetts, USA.
Kalpana GuptaVA Boston Healthcare System, West Roxbury, Massachusetts, USA Boston University School of Medicine, Boston, Massachusetts, USA National Center for Occupational Health and Infection Control, Gainesville, Florida, USA.
VA Boston Healthcare System · USBoston University · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few oral antibiotics exist for the empirical treatment of extended-spectrum β-lactamase (ESBL) urinary tract infections (UTI). In this study, we sought to determine the activity of fosfomycin against ESBL-producing uropathogens from patients at 3 Veterans Affairs (VA) facilities between 2010 and 2013. Among the ESBL uropathogens, 19.9% were fosfomycin resistant. Klebsiella species were more likely than Escherichia coli to be resistant (46% versus 4%; P < 0.001). Fosfomycin remains active against a majority of the ESBL uropathogens, although resistance among Klebsiella spp. was higher than that in previous reports.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesDrug Resistance, Multiple, BacterialEscherichia coliFosfomycinHospitals, VeteransHumansKlebsiellaMaleMassachusettsMicrobial Sensitivity TestsUrinary Tract InfectionsAnti-Bacterial Agentsbeta-LactamasesFosfomycin

Identifiers

PMID26596940
PMCPMC4750673
OpenAlexW2256265470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.