ArticleScientific reports2015
Universal behavior of hydrogels confined to narrow capillaries.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 54 citations in OpenAlex.
- Polymer solutions under steady solvent flow between two semipermeable interfaces.Macromolecules · 2025Article
- Progress of Research into Preformed Particle Gels for Profile Control and Water Shutoff Techniques.Gels (Basel, Switzerland) · 2024Review
- Effects of pH and Crosslinking Agent in the Evaluation of Hydrogels as Potential Nitrate-Controlled Release Systems.Polymers · 2023Article
- Fibrous hydrogels under biaxial confinement.Nature communications · 2022Article
- On the Determination of Mechanical Properties of Aqueous Microgels-Towards High-Throughput Characterization.Gels (Basel, Switzerland) · 2021Article
- Under pressure: Hydrogel swelling in a granular medium.Science advances · 2021Article
- Dynamics of Vesicles Driven Into Closed Constrictions by Molecular Motors.Bulletin of mathematical biology · 2020Article
- Bottlebrush Bridge between Soft Gels and Firm Tissues.ACS central science · 2020Article
- Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions.Scientific reports · 2019Article
- Microfluidic model systems used to emulate processes occurring during soft particle filtration.Scientific reports · 2019Article
- Transport mechanism of deformable micro-gel particle through micropores with mechanical properties characterized by AFM.Scientific reports · 2019Article
- Flow of Tunable Elastic Microcapsules through Constrictions.Scientific reports · 2017Article
- Dual-responsive and Multi-functional Plasmonic Hydrogel Valves and Biomimetic Architectures Formed with Hydrogel and Gold Nanocolloids.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Flow of soft matter objects through one-dimensional environments is important in industrial, biological and biomedical systems. Establishing the underlying principles of the behavior of soft matter in confinement can shed light on its performance in many man-made and biological systems. Here, we report an experimental and theoretical study of translocation of micrometer-size hydrogels (microgels) through microfluidic channels with a diameter smaller than an unperturbed microgel size. For microgels with different dimensions and mechanical properties, under a range of applied pressures, we established the universal principles of microgel entrance and passage through microchannels with different geometries, as well as the reduction in microgel volume in confinement. We also show a non-monotonic change in the flow rate of liquid through the constrained microgel, governed by its progressive confinement. The experimental results were in agreement with the theory developed for non-linear biaxial deformation of unentangled polymer gels. Our work has implications for a broad range of phenomena, including occlusion of blood vessels by thrombi and needle-assisted hydrogel injection in tissue engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.