Evidence map›Paper›PMID 26596400›Full record

Trial reportAmerican journal of ophthalmology2016

Postoperative Complications in the Ahmed Baerveldt Comparison Study During Five Years of Follow-up.

Donald L Budenz, William J Feuer, Keith Barton, Joyce Schiffman, Vital P Costa, David G Godfrey, Yvonne M Buys, Ahmed Baerveldt Comparison Study Group

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 6 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 6 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Outcomes of the Ahmed clearpath glaucoma drainage device in glaucoma: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Pooled it
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  4. Ahmed and baerveldt in glaucoma surgery: what is the safest choice? - a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  5. Metabolomics in Glaucoma: A Systematic Review.Investigative ophthalmology & visual science · 2021
    Pooled it
  6. Aqueous shunts for glaucoma.The Cochrane database of systematic reviews · 2017
    Pooled it
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  11. Intraluminal aspiration for Ahmed glaucoma valve tube obstruction.American journal of ophthalmology case reports · 2026
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Donald L BudenzDepartment of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina. Electronic address: dbudenz@med.unc.edu.
William J FeuerBascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
Keith BartonNIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital, London, United Kingdom; Division of Epidemiology and Genetics, Institute of Ophthalmology, University College London, London, United Kingdom.
Joyce SchiffmanBascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
Vital P CostaDepartment of Ophthalmology, University of Campinas, São Paulo, Brazil.
David G GodfreyGlaucoma Associates of Texas, Dallas, Texas.
Yvonne M BuysDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
Ahmed Baerveldt Comparison Study Group
University of Miami · USUniversity of North Carolina at Chapel Hill · USGlaucoma Associates of Texas · USMoorfields Eye Hospital NHS Foundation Trust · GBUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Toronto · CA

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
NEI NIH HHS P30 EY014801
6 · The paper itself

Abstract

purposeTo compare the late complications in the Ahmed Baerveldt Comparison Study during 5 years of follow-up.

designMulticenter, prospective randomized clinical trial.

methodssetting: Sixteen international clinical centers. STUDY POPULATION: Two hundred seventy-six subjects aged 18-85 years with previous intraocular surgery or refractory glaucoma with intraocular pressure of >18 mm Hg.

interventionsAhmed Glaucoma Valve FP7 or Baerveldt Glaucoma Implant BG 101-350.

main outcome measuresLate postoperative complications (beyond 3 months), reoperations for complications, and decreased vision from complications.

resultsLate complications developed in 56 subjects (46.8 ± 4.8 5-year cumulative % ± SE) in the Ahmed Glaucoma Valve group and 67 (56.3 ± 4.7 5-year cumulative % ± SE) in the Baerveldt Glaucoma Implant group (P = .082). The cumulative rates of serious complications were 15.9% and 24.7% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .034), although this was largely driven by subjects who had tube occlusions in the 2 groups (0.8% in the Ahmed Glaucoma Valve group and 5.7% in the Baerveldt Glaucoma Implant group, P = .037). Both groups had a relatively high incidence of persistent diplopia (12%) and corneal edema (20%), although half of the corneal edema cases were likely due to pre-existing causes other than the aqueous shunt. The incidence of tube erosion was 1% and 3% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .04).

conclusionsLong-term rates of vision-threatening complications and complications resulting in reoperation were higher in the Baerveldt Glaucoma Implant than in the Ahmed Glaucoma Valve group over 5 years of follow-up.

Indexed as

Postoperative ComplicationsAdolescentAdultAgedAged, 80 and overFemaleFollow-Up StudiesGlaucoma Drainage ImplantsGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedProspective StudiesProsthesis ImplantationReoperation

Identifiers

PMID26596400
PMCPMC4901387
OpenAlexW2176277423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.