Evidence map›Paper›PMID 26596360›Full record

Trial reportJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery2015

Clinical relevance of cone beam computed tomography in mandibular third molar removal: A multicentre, randomised, controlled trial.

H Ghaeminia, N L Gerlach, Th J M Hoppenreijs, M Kicken, J P Dings, W A Borstlap, T de Haan, S J Bergé, G J Meijer, T J Maal

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02071030 (The Efficacy of Cone Beam Computed Tomography), which is not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02071030 nacompletednot on this map

The Efficacy of Cone Beam Computed Tomography (CBCT) Compared to Panoramic Radiography Prior to Third Molar Removal; a Multicentre Randomised Controlled Trial

TypeinterventionalSponsorRadboud University Medical CenterRan2013 to 2014Enrolled477ConditionsInferior Alveolar Nerve InjuryArmsThird molar removal
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

H GhaeminiaDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands. Electronic address: hos.ghaeminia@gmail.com.
N L GerlachDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands. Electronic address: niekgerlach@hotmail.com.
Th J M HoppenreijsRijnstate Hospital Arnhem, Department of Oral and Maxillofacial Surgery, Wagnerlaan 55, 6815AD Arnhem, The Netherlands. Electronic address: hoppenreijs@me.com.
M KickenRijnstate Hospital Arnhem, Department of Oral and Maxillofacial Surgery, Wagnerlaan 55, 6815AD Arnhem, The Netherlands. Electronic address: marc.kicken@gmail.com.
J P DingsDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands. Electronic address: jeroen.dings@radboudumc.nl.
W A BorstlapDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands; ZBC Private Clinic Nijmegen, Oral and Maxillofacial Surgery, Groenewoudseweg 315, 6524 TX Nijmegen, The Netherlands. Electronic address: wilfred.borstlap@radboudumc.nl.
T de HaanRadboud University Medical Center, Department of Health Evidence, Geert Grooteplein-Noord 21, 6525 GA Nijmegen, The Netherlands. Electronic address: ton.dehaan@radboudumc.nl.
S J BergéDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands; ZBC Private Clinic Nijmegen, Oral and Maxillofacial Surgery, Groenewoudseweg 315, 6524 TX Nijmegen, The Netherlands. Electronic address: stefaan.berge@radboudumc.nl.
G J MeijerDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands; Radboud University Medical Center, Implantology & Periodontology, Phillips van Leydenlaan 25, 6525 EX Nijmegen, The Netherlands. Electronic address: gert.meijer@radboudumc.nl.
T J MaalDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands. Electronic address: thomas.maal@radboudumc.nl.
Radboud University Medical Center · NLRadboud University Nijmegen · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aims of this study were to investigate the effectiveness of cone beam computed tomography (CBCT) compared to panoramic radiography (PR), prior to mandibular third molar removal, in reducing patient morbidity, and to identify risk factors associated with inferior alveolar nerve (IAN) injury. MATERIAL AND

methodsThis multicentre, randomised, controlled trial was performed at three centres in the Netherlands. Adults with an increased risk for IAN injury, as diagnosed from PR, were included in the study. In one arm of the study, patients underwent an additional CBCT prior to third molar surgery. In a second arm of the study, no additional radiographs were acquired. The primary outcome measure was the number of patient-reported altered sensations 1 week after surgery. As secondary outcome measures, the number of patients with objective IAN injury, with long-term (>6 months) IAN injury, the occurrence of other postoperative complications, the Oral Health Related Quality of Life-14 (OHIP-14) questionnaire responses, postoperative pain (visual analogue scale score), duration of surgery, number of emergency visits, and number of missed days of work or study were scored.

resultsA total of 268 patients with 320 mandibular third molars were analysed according to the intention-to-treat principle. The overall incidence of IAN injury 1 week after surgery was 6.3%. No significant differences between CBCT and PR for temporary IAN injury (p = 0.64) and all other secondary outcomes were registered. A lingual position of the mandibular canal (MC) and narrowing, in which the diameter of the MC lumen was decreased at the contact area between the MC and the roots, were significant risk factors for temporary IAN injury.

conclusionAlthough CBCT is a valuable diagnostic adjunct for identification of an increased risk for IAN injury, the use of CBCT does not translate into a reduction of IAN injury and other postoperative complications, after removal of the complete mandibular third molar. In these selected cases of a high risk for IAN injury, an alternative strategy, such as monitoring or a coronectomy, might be more appropriate. (http://clinicaltrials.gov, NCT02071030).

Indexed as

Cone-Beam Computed TomographyHumansMolar, ThirdNetherlandsQuality of LifeRadiography, PanoramicTooth ExtractionTooth, ImpactedTrigeminal Nerve InjuriesComplicationsDry socketMandibular nervePanoramic radiographyQuality of lifeThree-dimensional imaging

Identifiers

PMID26596360
OpenAlexW2172496859

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.