Evidence map›Paper›PMID 26595744›Full record

ArticleEnvironmental toxicology and pharmacology2015

A pilot study of low-moderate drinking water arsenic contamination and chronic diseases among reproductive age women in Timiş County, Romania.

Celeste D Butts, Michael S Bloom, Iulia A Neamtiu, Simona Surdu, Cristian Pop, Doru Anastasiu, Edward F Fitzgerald, Eugen S Gurzau

Abstract read
In one paragraph

Article in Environmental toxicology and pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Celeste D ButtsDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA.
Michael S BloomDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA; Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA. Electronic address: mbloom@albany.edu.
Iulia A NeamtiuEnvironmental Health Center, Cluj-Napoca, Romania.
Simona SurduDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA.
Cristian PopEnvironmental Health Center, Cluj-Napoca, Romania.
Doru AnastasiuUniversity of Medicine and Pharmacy "Victor Babes", Timişoara, Romania; Gynecology Department of the Emergency County Hospital, Timişoara, Romania.
Edward F FitzgeraldDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA; Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA.
Eugen S GurzauEnvironmental Health Center, Cluj-Napoca, Romania; University of Medicine and Pharmacy "Iuliu Haţieganu", Cluj-Napoca, Romania.
University at Albany, State University of New York · USIuliu Hațieganu University of Medicine and Pharmacy · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

Developmental Infrastructure CoreR24HD044943 · NICHD · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI GAGE, TIMOTHY B · 2004 to 2016
$4.8M
Arsenic Contaminated Water Consumption & Spontaneous Pregnancy Loss in RomaniaR03ES020446 · NIEHS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI BLOOM, MICHAEL S · 2011 to 2012
$151k
NICHD NIH HHS R24 HD044943NIEHS NIH HHS R03 ES020446NIEHS NIH HHS R03ES020446
6 · The paper itself

Abstract

We conducted a pilot study of associations between drinking water contaminated by inorganic arsenic (iAs), mostly <10 μg/L, and self-reported chronic diseases in 297 pregnant women. Adjusted for confounding variables, we identified a positive association between iAs and heart disease (OR = 1.63, 95%CI 0.81-3.04, p = 0.094), which was stronger for women living at their current residence ≥ 10 years (OR = 2.47, 95%CI 0.87-10.43, p = 0.058). Confounder-adjusted associations were also suggested for iAs with kidney disease (OR = 1.32, 95%CI 0.77-2.21, p = 0.265) and with high blood pressure (OR = 1.36, 95%CI 0.68-2.39, p = 0.300). A post hoc power analysis indicated the need for a larger study with more statistical power.

Indexed as

AdultArsenicChronic DiseaseDrinking WaterFemaleHumansPilot ProjectsPregnancyRomaniaYoung AdultArsenicDrinking WaterArsenicBlood pressureDrinking waterHeart diseaseKidney diseaseThyroid disorder

Identifiers

PMID26595744
PMCPMC4679485
OpenAlexW2139576021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.