ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2015
Altered Contralateral Auditory Cortical Morphology in Unilateral Sudden Sensorineural Hearing Loss.
Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- Disrupted Cross-Scale Network Associated With Cognitive-Emotional Disorders in Sudden Sensorineural Hearing Loss.CNS neuroscience & therapeutics · 2025Article
- Somatosensory cross-modal activation and changes in cortical somatosensory evoked potential responses in single-sided deafness: an EEG study.Frontiers in neuroscience · 2025Article
- Global trends and hotspots in research for sudden hearing loss over the past two decades: a bibliometric and visualization analyses.Frontiers in neurology · 2025Review
- Altered static and dynamic intrinsic brain activity in unilateral sudden sensorineural hearing loss.Frontiers in neuroscience · 2023Article
- Abnormal regional signal in the left cerebellum as a potential neuroimaging biomarker of sudden sensorineural hearing loss.Frontiers in psychiatry · 2022Article
- Intrinsic brain activity reorganization contributes to long-term compensation of higher-order hearing abilities in single-sided deafness.Frontiers in neuroscience · 2022Article
- Abnormal cerebellar network and effective connectivity in sudden and long-term sensorineural hearing loss.Frontiers in aging neuroscience · 2022Article
- [A preliminary study on the negative wave mismatch in patients with unilateral total sudden deafness].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021Article
- Disrupted Topological Organization in White Matter Networks in Unilateral Sudden Sensorineural Hearing Loss.Frontiers in neuroscience · 2021Article
- Imaging Parameters of the Ipsilateral Medial Geniculate Body May Predict Prognosis of Patients with Idiopathic Unilateral Sudden Sensorineural Hearing Loss on the Basis of Diffusion Spectrum Imaging.AJNR. American journal of neuroradiology · 2021Article
- Ear-Specific Hemispheric Asymmetry in Unilateral Deafness Revealed by Auditory Cortical Activity.Frontiers in neuroscience · 2021Article
- Functional Magnetic Resonance Imaging Reveals Early Connectivity Changes in the Auditory and Vestibular Cortices in Idiopathic Sudden Sensorineural Hearing Loss With Vertigo: A Pilot Study.Frontiers in human neuroscience · 2021Article
- Cortical reorganization following auditory deprivation predicts cochlear implant performance in postlingually deaf adults.Human brain mapping · 2021Article
- Aberrant Functional and Causal Connectivity in Acute Tinnitus With Sensorineural Hearing Loss.Frontiers in neuroscience · 2020Article
- Inhibition of Brain Area and Functional Connectivity in Idiopathic Sudden Sensorineural Hearing Loss With Tinnitus, Based on Resting-State EEG.Frontiers in neuroscience · 2019Article
- Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus.Frontiers in neuroscience · 2019Article
- Abnormal brain structure as a potential biomarker for venous erectile dysfunction: evidence from multimodal MRI and machine learning.European radiology · 2018Article
- Altered functional networks in long-term unilateral hearing loss: A connectome analysis.Brain and behavior · 2018Article
- Assessment of balance and vestibular functions in patients with idiopathic sudden sensorineural hearing loss.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2017Article
- A novel method of quantifying brain atrophy associated with age-related hearing loss.NeuroImage. Clinical · 2017Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the cerebral gray matter volume alterations in unilateral sudden sensorineural hearing loss patients within the acute period by the voxel-based morphometry method, and to determine if hearing impairment is associated with regional gray matter alterations in unilateral sudden sensorineural hearing loss patients. STUDY
designProspective case study.
settingTertiary class A teaching hospital. PATIENTS: Thirty-nine patients with left-side unilateral sudden sensorineural hearing loss and 47 patients with right-side unilateral sudden sensorineural hearing loss.
interventionDiagnostic.
main outcome measureTo compare the regional gray matter of unilateral sudden sensorineural hearing loss patients and healthy control participants.
resultsCompared with control groups, patients with left side unilateral sudden sensorineural hearing loss had significant gray matter reductions in the right middle temporal gyrus and right superior temporal gyrus, whereas patients with right side unilateral sudden sensorineural hearing loss showed gray matter decreases in the left superior temporal gyrus and left middle temporal gyrus. A significant negative correlation with the duration of the sudden sensorineural hearing loss (R = -0.427, p = 0.012 for left-side unilateral SSNHL and R = -0.412, p = 0.013 for right-side unilateral SSNHL) was also found in these brain areas. There was no region with increased gray matter found in both groups of unilateral sudden sensorineural hearing loss patients.
conclusionsThis study confirms that detectable decreased contralateral auditory cortical morphological changes have occurred in unilateral SSNHL patients within the acute period by voxel-based morphometry methods. The gray matter volumes of these brain areas also perform a negative correlation with the duration of the disease, which suggests a gradual brain structural impairment after the progression of the disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.