ArticleJournal of abnormal psychology2015
Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress.
Article in Journal of abnormal psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 228 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
228 citing papers in PubMed, 7 syntheses or guidelines pooled it, 434 citations in OpenAlex.
- The association between parent-adolescent conflicts and depressive mood: a systematic review and meta-analysis.BMC psychology · 2025Pooled it
- Regulatory Role of PFC Corticotropin-Releasing Factor System in Stress-Associated Depression Disorders: A Systematic Review.Cellular and molecular neurobiology · 2023Pooled it
- Associations Between Pubertal Stage and Depression: A Systematic Review of the Literature.Child psychiatry and human development · 2023Pooled it
- Family therapy for adolescents with depression and suicidal ideation: A systematic review and meta-analysis.Clinical child psychology and psychiatry · 2023Pooled it
- Polygenic Risk for Major Depression Interacts with Parental Criticism in Predicting Adolescent Depressive Symptom Development.Journal of youth and adolescence · 2021Pooled it
- Exploring the Impact of COVID-19 on Mental Health Outcomes in Children and Adolescents: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Psychological Mediators of the Association Between Childhood Emotional Abuse and Depression: A Systematic Review.Frontiers in psychiatry · 2020Pooled it
- Supporting healthy development in adolescence: Technology-supported cooperative learning can reduce stress and increase sleep quality.Journal of school psychology · 2025Trial
- Internal Consistency and Validity of a Short Spanish Version (10-Items) of the Center for Epidemiological Studies Depression Scale for Children and Adolescents (CES-DC).Depression and anxiety · 2024Trial
- Effects of personalized depression prevention on anxiety through 18-month follow-up: A randomized controlled trial.Behaviour research and therapy · 2022Trial
- Personalized Depression Prevention: A Randomized Controlled Trial to Optimize Effects Through Risk-Informed Personalization.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Trial
- Reducing Stress and Preventing Depression (RESPOND): Randomized Controlled Trial of Web-Based Rumination-Focused Cognitive Behavioral Therapy for High-Ruminating University Students.Journal of medical Internet research · 2019Trial
- The Depression Prevention Initiative: Impact on Adolescent Internalizing and Externalizing Symptoms in a Randomized Trial.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2019Trial
- Emotion regulation and its relation to symptoms of anxiety and depression in children aged 8-12 years: does parental gender play a differentiating role?BMC psychology · 2018Trial
- Mapping emotion regulation profiles in adolescence and examining their associations with mental health outcomes.Child and adolescent psychiatry and mental health · 2026Article
- A Shelter for the Heart: The Impact of Teacher Quality on Students' Mental Health.Health economics · 2026Article
- Examining early inhibitory control and emotion regulation as predictors of childhood internalizing and externalizing problems: A longitudinal study.JCPP advances · 2026Article
- Geospatial Indices of Neighborhood Environment and Preadolescent Behavioral Health Screening in Primary Care.The Journal of pediatrics · 2026Article
- The Relationship Between Chronotype and Depression Among Adolescents: The Mediating Role of Bedtime Procrastination and the Moderating Role of Parental Psychological Control.Behavioral sciences (Basel, Switzerland) · 2026Article
- Mental health trajectory groups: Family income, neighborhood disadvantage, and role of the school environment.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
168 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Depression is a debilitating mental illness with clear developmental patterns from childhood through late adolescence. Here, we present data from the Gene Environment Mood (GEM) study, which used an accelerated longitudinal cohort design with youth (N = 665) starting in 3rd, 6th, and 9th grades, and a caretaker, who were recruited from the general community, and were then assessed repeatedly through semistructured diagnostic interviews every 6 months over 3 years (7 waves of data) to establish and then predict trajectories of depression from age 8 to 18. First, we demonstrated that overall prevalence rates of depression over time, by age, gender, and pubertal status, in the GEM study closely match those trajectories previously obtained in past developmental epidemiological research. Second, we tested whether a genetic vulnerability-stress model involving 5-HTTLPR and chronic peer stress was moderated by developmental factors. Results showed that older aged adolescents with SS/SL genotype, who experienced higher peer chronic stress over 3 years, were the most likely to be diagnosed with a depressive episode over time. Girls experiencing greater peer chronic stress were the most likely to develop depression. This study used repeated assessments of diagnostic interviewing in a moderately large sample of youth over 3 years to show that depression rates increase in middle to late adolescence, or postpubertally, and that the gender difference in depression emerges earlier in adolescence (age 12.5), or postpubertally. Additionally, genetically susceptible older adolescents who experience chronic peer stress were the most likely to become depressed over time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.