Evidence map›Paper›PMID 26595464›Full record

ArticleJournal of abnormal psychology2016

Altered subjective reward valuation among drug-deprived heavy marijuana users: Aversion to uncertainty.

Kathryn R Hefner, Mark J Starr, John J Curtin

Abstract read
In one paragraph

Article in Journal of abnormal psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Neural underpinnings of maladaptive decision-making in addictions.Pharmacology, biochemistry, and behavior · 2018
    Review
  6. Review
  7. Altered subjective reward valuation among female heavy marijuana users.Experimental and clinical psychopharmacology · 2017
    Article
  8. The effects of alcohol on emotion in social drinkers.Behaviour research and therapy · 2017
    Review
  9. Intolerance of uncertainty and insula activation during uncertain reward.Cognitive, affective & behavioral neuroscience · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn R HefnerMental Illness Research, Education, and Clinical Centers (MIRECC), VA Connecticut Healthcare System.
Mark J StarrDepartment of Psychology, University of Wisconsin-Madison.
John J CurtinDepartment of Psychology, University of Wisconsin-Madison.

Funding

TRAINING PROGRAM IN EMOTION RESEARCHT32MH018931 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI Richard J Davidson · 1989 to 2026
$11.6M
Anxiety and Biased Decision-Making in Drug-Deprived Marijuana UsersF31DA032184 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI HEFNER, KATHRYN ROSE · 2011 to 2013
$90k
NIDA NIH HHS DA032184NIDA NIH HHS F31 DA032184NIMH NIH HHS T32 MH018931
6 · The paper itself

Abstract

Marijuana is the most commonly used illicit drug in the United States and its use is rising. Nonetheless, scientific efforts to clarify the risk for addiction and other harm associated with marijuana use have been lacking. Maladaptive decision-making is a cardinal feature of addiction that is likely to emerge in heavy users. In particular, distorted subjective reward valuation related to homeostatic or allostatic processes has been implicated for many drugs of abuse. Selective changes in responses to uncertainty have been observed in response to intoxication and deprivation from various drugs of abuse. To assess for these potential neuroadaptive changes in reward valuation associated with marijuana deprivation, we examined the subjective value of uncertain and certain rewards among deprived and nondeprived heavy marijuana users in a behavioral economics decision-making task. Deprived users displayed reduced valuation of uncertain rewards, particularly when these rewards were more objectively valuable. This uncertainty aversion increased with increasing quantity of marijuana use. These results suggest comparable decision-making vulnerability from marijuana use as other drugs of abuse, and highlights targets for intervention.

Indexed as

RewardUncertaintyAdolescentAdultAffectDecision MakingFemaleHumansMaleMarijuana AbuseMarijuana SmokingNeuropsychological TestsReaction TimeYoung Adult

Identifiers

PMID26595464
PMCPMC4701603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.