ArticleNature methods2016
NeuroGPS-Tree: automatic reconstruction of large-scale neuronal populations with dense neurites.
Article in Nature methods, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed.
- A quantitative and precision‑oriented neuronal reconstruction approach based on data grading.Brain informatics · 2026Article
- A Million-Scale, Difficulty-Stratified Optical-Microscopy Image Annotation for Neuron Reconstruction.Scientific data · 2026Article
- Long-range circuit of the mouse spinal trigeminal nucleus caudalis.The journal of headache and pain · 2026Article
- High-Resolution Single-Neuron Reconstruction Analysis in Golgi-Stained Brain Tissues.Cell proliferation · 2026Article
- Automatic and accurate reconstruction of long-range axonal projections of single-neuron in mouse brain.eLife · 2025Article
- Image enhancement network based on fiber topology-preserving multi-module fusion for neuron reconstruction.Biomedical optics express · 2025Article
- Parvalbumin Neurons in the Basal Forebrain Projecting to the Mammillary Nucleus Ameliorate Age-Related Cognitive Decline.International journal of molecular sciences · 2025Article
- Layer-specific input to medial prefrontal cortex is linked to stress susceptibility.Translational psychiatry · 2025Article
- A neuronal imaging dataset for deep learning in the reconstruction of single-neuron axons.Frontiers in neuroinformatics · 2025Article
- Gapr for large-scale collaborative single-neuron reconstruction.Nature methods · 2024Article
- A hierarchically annotated dataset drives tangled filament recognition in digital neuron reconstruction.Patterns (New York, N.Y.) · 2024Article
- High-throughput analysis of dendrite and axonal arbors reveals transcriptomic correlates of neuroanatomy.Nature communications · 2024Article
- Automated neuronal reconstruction with super-multicolour Tetbow labelling and threshold-based clustering of colour hues.Nature communications · 2024Article
- Integrated platform for multiscale molecular imaging and phenotyping of the human brain.Science (New York, N.Y.) · 2024Article
- Connecto-informatics at the mesoscale: current advances in image processing and analysis for mapping the brain connectivity.Brain informatics · 2024Review
- Quantifying morphologies of developing neuronal cells using deep learning with imperfect annotations.IBRO neuroscience reports · 2024Article
- A modular framework for multi-scale tissue imaging and neuronal segmentation.Nature communications · 2024Article
- Subregion preference in the long-range connectome of pyramidal neurons in the medial prefrontal cortex.BMC biology · 2024Article
- Complete Neuron Reconstruction Based on Branch Confidence.Brain sciences · 2024Article
- NIEND: neuronal image enhancement through noise disentanglement.Bioinformatics (Oxford, England) · 2024Article
18 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reconstruction of neuronal populations, a key step in understanding neural circuits, remains a challenge in the presence of densely packed neurites. Here we achieved automatic reconstruction of neuronal populations by partially mimicking human strategies to separate individual neurons. For populations not resolvable by other methods, we obtained recall and precision rates of approximately 80%. We also demonstrate the reconstruction of 960 neurons within 3 h.
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