ArticleFrontiers in plant science2015
Cadmium affects microtubule organization and post-translational modifications of tubulin in seedlings of soybean (Glycine max L.).
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Thyme Oil Alleviates Cadmium-Induced Disturbances in Mitotic Activity, Cytoskeletal Organization and H3T3/H3S10 Phosphorylation inInternational journal of molecular sciences · 2026Article
- Alterations in the Anatomy and Ultrastructure of Leaf Blade in Norway Maple (Plants (Basel, Switzerland) · 2024Article
- Detection of heavy metal contamination in Batlama Stream (Turkiye) and the potential toxicity profile.Scientific reports · 2023Article
- Nitric oxide promotes adventitious root formation in cucumber under cadmium stress through improving antioxidant system, regulating glycolysis pathway and polyamine homeostasis.Frontiers in plant science · 2023Article
- Screening the toxicity profile and genotoxicity mechanism of excess manganese confirmed by spectral shift.Scientific reports · 2022Article
- Mitochondria Specific Antioxidant, MitoTEMPO, Modulates Cd Uptake and Oxidative Response of Soybean Seedlings.Antioxidants (Basel, Switzerland) · 2022Article
- Pieces of evidence of enhanced cellulose biosynthesis in the low-Cd cultivar and high expression level of transportation genes in the high-Cd cultivar of Lactuca sativa.Environmental science and pollution research international · 2022Article
- Article
- Plant Recovery after Metal Stress-A Review.Plants (Basel, Switzerland) · 2021Review
- CAX3 (cation/proton exchanger) mediates a Cd tolerance by decreasing ROS through Ca elevation in Arabidopsis.Plant molecular biology · 2021Article
- Cadmium toxicity and its relationship with disturbances in the cytoskeleton, cell cycle and chromosome stability.Ecotoxicology (London, England) · 2019Article
- Quantitative proteomic analysis of tomato genotypes with differential cadmium tolerance.Environmental science and pollution research international · 2019Article
- Article
- Root Hair Single Cell Type Specific Profiles of Gene Expression and Alternative Polyadenylation Under Cadmium Stress.Frontiers in plant science · 2019Article
- Review
- Tubulin C-terminal Post-translational Modifications Do Not Occur in Wood Forming Tissue ofFrontiers in plant science · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) is a non-essential heavy metal, toxic to all living organisms. The microtubule (MT) cytoskeleton appears to be one of the main targets of Cd action. In this study we present, with the use of various immunological approaches, the effect of Cd at moderate (85 μM) and high (170 μM) concentrations on the structure and functioning of the MT cytoskeleton in the root cells of soybean seedlings. As the result of heavy metal action, root growth was significantly diminished and was accompanied by a reduction in mitotic activity and disturbance in the structure of the MT arrays, including randomization of the cortical MT arrangement, distorted mitotic arrays and complete depolymerization of the MTs. Biochemical analysis revealed decreased levels of various α- and β-tubulin isoforms with a parallel down-regulation of most examined α-tubulin genes. Simultaneously, Cd treatment led to differentiated changes in the level of tubulin post-translational modifications, including tyrosination, detyrosination, acetylation, and polyglutamylation. Decreased tyrosination and polyglutamylation of particular tubulin isoforms accompanied by increase in the level of specific detyrosinated and acetylated isoforms implies augmented stability and reduced turnover of the MTs during stress conditions. Taken together, the obtained results indicate the significant impact of Cd on gene expression levels and subsequent post-translational processing of tubulin, which may be related to the impairment of MT cytoskeleton functioning in root cells.
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