ArticleScientific reports2015
Multiple Sources of Infection and Potential Endemic Characteristics of the Large Outbreak of Dengue in Guangdong in 2014.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Human-animal interfaces and zoonotic disease risks in China: a review of contact behaviors and risk communication.Science in One Health · 2026Review
- Temporal shifts in dengue epidemic in Guangdong Province before and during the COVID-19 pandemic: a Bayesian model study from 2012 to 2022.PLoS neglected tropical diseases · 2025Article
- Sofosbuvir Suppresses the Genome Replication of DENV1 in Human Hepatic Huh7 Cells.International journal of molecular sciences · 2024Article
- The Origin and Molecular Epidemiology of Dengue Fever in Hainan Province, China, 2019.Frontiers in microbiology · 2021Article
- Dengue Fever Outbreaks Caused by Varied Serotype Dengue Virus - Guangdong Province, China, 2019.China CDC weekly · 2020Article
- Epidemiological and Evolutionary Analysis of Dengue-1 Virus Detected in Guangdong during 2014: Recycling of Old and Formation of New Lineages.The American journal of tropical medicine and hygiene · 2019Article
- Multiple Lineages of Dengue Virus Serotype 2 Cosmopolitan Genotype Caused a Local Dengue Outbreak in Hangzhou, Zhejiang Province, China, in 2017.Scientific reports · 2019Article
- Inter-annual variation in seasonal dengue epidemics driven by multiple interacting factors in Guangzhou, China.Nature communications · 2019Article
- Dengue seroprevalence in a cohort of schoolchildren and their siblings in Yucatan, Mexico (2015-2016).PLoS neglected tropical diseases · 2018Article
- Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016.PLoS neglected tropical diseases · 2018Article
- Dengue serosurvey after a 2-month long outbreak in Nîmes, France, 2015: was there more than met the eye?Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- [Larvicidal activity of recombinant Escherichia coli expressing scorpion neurotoxin AaIT or B.t.i toxin Cyt2Ba against mosquito larvae and formulations for enhancing the effects].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017Article
- Epidemiological and molecular characteristics of emergent dengue virus in Yunnan Province near the China-Myanmar-Laos border, 2013-2015.BMC infectious diseases · 2017Article
- Temporal Topic Modeling to Assess Associations between News Trends and Infectious Disease Outbreaks.Scientific reports · 2017Article
- Analysis of heterogeneous dengue transmission in Guangdong in 2014 with multivariate time series model.Scientific reports · 2016Article
- Dengue research: a bibliometric analysis of worldwide and Arab publications during 1872-2015.Virology journal · 2016Article
- Concurrent infection of dengue virus with malaria parasites among outpatients attending healthcare facilities in Benin city, Nigeria.Porto biomedical journalArticle
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12 authors.
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Abstract
A large outbreak of dengue, with the most documented cases, occurred in Guangdong China in 2014. Epidemiological studies and phylogenetic analysis of the isolated dengue virus (DENV) showed this outbreak was attributed to multiple sources and caused by at least two genotypes of DENV-1 (Genotypes I and III) and two genotypes of DENV-2 (Cosmopolitan and Asian I Genotypes). A retrospective review and phylogenetic analysis of DENV isolated in Guangdong showed that DENV-1 Genotype I strains were reported continuously during 2004-2014, Genotype III strains were reported during 2009-2014 ; DENV-2 Cosmopolitan and Asian I Genotype strains were reported continuously during 2012-2014. At least 45,171 cases were reported in this outbreak, with 65.9% of the patients in the 21-55-year-old group. A trend toward a decrease in the daily newly emerged cases lagged by approximately 20 days compared with the mosquito density curve. Several epidemiological characteristics of this outbreak and the stably sustained serotypes and genotypes of DENV isolated in Guangdong suggest that Guangdong has been facing a threat of transforming from a dengue epidemic area to an endemic area. The high temperature, drenching rain, rapid urbanization, and pandemic of dengue in Southeast Asia may have contributed to this large outbreak of dengue.
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