Evidence map›Paper›PMID 26590799›Full record

ArticleActa psychiatrica Scandinavica2016

Sleep problems in bipolar disorders: more than just insomnia.

M K Steinan, J Scott, T V Lagerberg, I Melle, O A Andreassen, A E Vaaler, G Morken

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta psychiatrica Scandinavica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Results of a pilot randomized controlled trial of CBT-I for veterans with serious mental illness and insomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Bipolar Disorder, Circadian Rhythm and Clock Genes.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

M K SteinanFaculty of Medicine, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
J ScottAcademic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle, UK.
T V LagerbergNORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway.
I MelleNORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
O A AndreassenNORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway.
A E VaalerFaculty of Medicine, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
G MorkenFaculty of Medicine, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
Norwegian University of Science and Technology · NOOslo University Hospital · NONewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSleep problems in bipolar disorder (BD) are common, but reported rates vary from 10% to 80%, depending on definitions, methodologies and management of potential confounding factors. This multicenter study seeks to address these issues and also compares BD cases with Hypersomnia as well as the more commonly investigated Insomnia and No Sleep Problem groups.

methodA cross-sectional comparison of sleep profiles in 563 BD I and II individuals who participated in a structured assessment of demographic, clinical, illness history and treatment variables.

resultsOver 40% cases met criteria for Insomnia and 29% for Hypersomnia. In univariate analysis, Insomnia was associated with BD II depression whilst Hypersomnia was associated with BD I depression or euthymia. After controlling for confounders and covariates, it was demonstrated that Hypersomnia cases were significantly more likely to be younger, have BD I and be prescribed antidepressants whilst Insomnia cases had longer illness durations and were more likely to be prescribed benzodiazepines and hypnotics.

conclusionWhilst Insomnia symptoms are common in BD, Hypersomnia is a significant, frequently underexplored problem. Detailed analyses of large representative clinical samples are critical to extending our knowledge of differences between subgroups defined by sleep profile.

Indexed as

AdultBipolar DisorderComorbidityCross-Sectional StudiesDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedNorwaySleep Initiation and Maintenance Disordersbipolar I disorderbipolar II disorderhypersomniainsomniasleep

Identifiers

PMID26590799
PMCPMC5063196
OpenAlexW2179656055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.