Evidence map›Paper›PMID 26590577›Full record

ArticleBiomolecular NMR assignments2016

Sequence-specific 1H, 13C and 15N backbone resonance assignments of the plakin repeat domain of human envoplakin.

Mark Jeeves, Claudia Fogl, Caezar Al-Jassar, Martyn Chidgey, Michael Overduin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecular NMR assignments, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mark JeevesHenry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Claudia FoglHenry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Caezar Al-JassarMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Martyn ChidgeySchool of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Michael OverduinHenry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. overduin@ualberta.ca.
University of Birmingham · GBMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_UP_1201/3Wellcome Trust
6 · The paper itself

Abstract

The plakin repeat domain is a distinctive hallmark of the plakin superfamily of proteins, which are found within all epithelial tissues. Plakin repeat domains mediate the interactions of these proteins with the cell cytoskeleton and are critical for the maintenance of tissue integrity. Despite their biological importance, no solution state resonance assignments are available for any homologue. Here we report the essentially complete (1)H, (13)C and (15)N backbone chemical shift assignments of the singular 22 kDa plakin repeat domain of human envoplakin, providing the means to investigate its interactions with ligands including intermediate filaments.

Indexed as

Nuclear Magnetic Resonance, BiomolecularRepetitive Sequences, Amino AcidAmino Acid SequenceHumansMembrane ProteinsPlakinsProtein PrecursorsenvoplakinMembrane ProteinsPlakinsProtein PrecursorsBackbone resonance assignmentCornified envelopeCytoskeletonEnvoplakinPlakinPlakin repeat domain

Identifiers

PMID26590577
PMCPMC4788679
OpenAlexW2175873762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.