Evidence map›Paper›PMID 26590567›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2016

Comparison of quadriceps muscle volume after unilateral total knee arthroplasty with and without tourniquet use.

Olcay Guler, Mahir Mahirogullari, Mehmet Isyar, Ahmet Piskin, Sercan Yalcin, Serhat Mutlu, Bünyamin Sahin

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03473106 (Effect of the Use of Tourniquet in the Thigh), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03473106 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effect of the Use of Tourniquet in the Thigh: a Biomechanical Analysis on the Muscular Function of the Quadriceps in the Postoperative Period.

TypeinterventionalSponsorUniversity of ChileRan2018 to 2020Enrolled30ConditionsPneumatic Tourniquet, Muscle WeaknessArmsPneumatic tourniquet use
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Olcay GulerOrthopedics and Traumatology Department, Medical Faculty, Medipol University, Atatürk Bulvarı. No:27 Unkapani, Fatih, 34083, Istanbul, Turkey. olcayguler77@gmail.com.
Mahir MahirogullariOrthopedics and Traumatology Department, Medical Faculty, Medipol University, Atatürk Bulvarı. No:27 Unkapani, Fatih, 34083, Istanbul, Turkey.
Mehmet IsyarOrthopedics and Traumatology Department, Medical Faculty, Medipol University, Atatürk Bulvarı. No:27 Unkapani, Fatih, 34083, Istanbul, Turkey.
Ahmet PiskinOrthopedics and Traumatology Department, Medical Faculty, Ondokuz Mayıs University, Samsun, Turkey.
Sercan YalcinOrthopedics and Traumatology Department, Medical Faculty, Medipol University, Atatürk Bulvarı. No:27 Unkapani, Fatih, 34083, Istanbul, Turkey.
Serhat MutluOrthopedics and Traumatology Department, Kanuni Sultan Suleyman Training Hospital, Istanbul, Turkey.
Bünyamin SahinAnatomy Department, Medical Faculty, Ondokuz Mayıs University, Samsun, Turkey.
Istanbul Medipol University · TROndokuz Mayıs University · TRİstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDetermination of the effect of tourniquet use in total knee arthroplasty (TKA) on thigh and quadriceps muscle volume using magnetic resonance imaging (MRI).

methodsA total of 148 knees of 74 patients (mean age 66.5 ± 4.8 years; female/male, 62/12) with bilateral primary varus gonarthrosis underwent unilateral TKA with a tourniquet (Group A, n = 35) or without a tourniquet (Group B, n = 39). The total thigh volume and connective, bone, and muscle tissue volumes were stereologically measured on preoperative and postoperative MRI. The Knee Society Score (KSS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score were calculated to evaluate functional outcomes.

resultsAfter TKA, the knees of patients in Group A exhibited a significant decrease in all tissue measurements, except bone tissue volume; however, the knees of patients in Group B exhibited no significant difference in tissue measurements. Although no difference was found between the operated and contralateral non-operated thighs (4076.9 and 4073.4 cm(3), respectively) in Group B postoperatively at 1 month (p > 0.05), the operated thighs had lost 20 % of its volume in Group A postoperatively at 1 month (p < 0.001). A significant difference was found in all tissue measurements, except the connective and bone tissue volumes of the thigh between the operated and contralateral non-operated knees in Group A. No significant difference was identified between the operated and contralateral non-operated knees in Group B. The total WOMAC score was significantly higher, and the total KSS was significantly lower in Group A than in Group B during the postoperative follow-up period of 1-6 months (p < 0.001 for all) but not 12 months (n.s.).

conclusionTourniquet use in TKA decreases the thigh and quadriceps muscle volumes and postoperatively delays the recovery of knee function. Therefore, caution should be exercised for tourniquet use during TKA in daily clinical practice and using alternative methods for tourniquet application in preventing intraoperative blood loss. LEVEL OF EVIDENCE: III.

Indexed as

AgedArthroplasty, Replacement, KneeBlood Loss, SurgicalFemaleHumansJoint DiseasesKnee JointMagnetic Resonance ImagingMaleMiddle AgedMuscle, SkeletalOrgan SizeOsteoarthritis, KneePostoperative PeriodQuadriceps MuscleThighAtrophyMagnetic resonance imagingQuadriceps muscleQuantitative analysisTotal knee arthroplastyTotal knee replacementTourniquet use

Identifiers

PMID26590567
OpenAlexW2180644813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.