Evidence map›Paper›PMID 26590403›Full record

ArticleNucleic acids research2016

SBR-Blood: systems biology repository for hematopoietic cells.

Jens Lichtenberg, Elisabeth F Heuston, Tejaswini Mishra, Cheryl A Keller, Ross C Hardison, David M Bodine

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jens LichtenbergNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA lichtenbergj@mail.nih.gov.ORCID http://orcid.org/0000-0002-0023-4937
Elisabeth F HeustonNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Tejaswini MishraDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
Cheryl A KellerDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
Ross C HardisonDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.
David M BodineNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

Funding

Hematopoietic Stem Cell BiologyZIAHG000083 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BODINE, DAVID M. · 2009 to 2022
$12.1M
Red Cell BiologyZIAHG200339 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BODINE, DAVID M. · 2009 to 2022
$11.8M
6 · The paper itself

Abstract

Extensive research into hematopoiesis (the development of blood cells) over several decades has generated large sets of expression and epigenetic profiles in multiple human and mouse blood cell types. However, there is no single location to analyze how gene regulatory processes lead to different mature blood cells. We have developed a new database framework called hematopoietic Systems Biology Repository (SBR-Blood), available online at http://sbrblood.nhgri.nih.gov, which allows user-initiated analyses for cell type correlations or gene-specific behavior during differentiation using publicly available datasets for array- and sequencing-based platforms from mouse hematopoietic cells. SBR-Blood organizes information by both cell identity and by hematopoietic lineage. The validity and usability of SBR-Blood has been established through the reproduction of workflows relevant to expression data, DNA methylation, histone modifications and transcription factor occupancy profiles.

Indexed as

Databases, GeneticAnimalsDNA MethylationEpigenesis, GeneticGene Expression ProfilingHematopoiesisHematopoietic Stem CellsHumansMiceSystems Biology

Identifiers

PMID26590403
PMCPMC4702891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.