Evidence map›Paper›PMID 26589907›Full record

Trial reportHaematologica2016

Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease.

Kim-Lien Nguyen, Xin Tian, Shoaib Alam, Alem Mehari, Steve W Leung, Catherine Seamon, Darlene Allen, Caterina P Minniti, Vandana Sachdev, Andrew E Arai and 1 more

Abstract readClinical TrialLetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Haematologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kim-Lien NguyenCardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, CA, USA.
Xin TianOffice of Biostatistics Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA.
Shoaib AlamCardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
Alem MehariSickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Howard University College of Medicine, Washington, DC, USA.
Steve W LeungCardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY, USA.
Catherine SeamonSickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA.
Darlene AllenSickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA.
Caterina P MinnitiSickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Hematology/Oncology, Sickle Cell Center, Montefiore Medical Center, New York, NY, USA.
Vandana SachdevCardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
Andrew E AraiCardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
Gregory J KatoSickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Hematology/Oncology and Adult Sickle Cell Center of Excellence, University of Pittsburgh, PA, USA katogj@upmc.edu.

Funding

Technical Development of Diagnostic Cardiovascular MRIZIAHL004607 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2009 to 2020
$25.3M
Quantification of Myocardial PerfusionZIAHL006137 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2011 to 2020
$9.4M
Advanced Cardiovascular Imaging FellowshipZIEHL006139 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2011 to 2020
$8.8M
Clinical Advanced Cardiovascular ImagingZIDHL006140 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW · 2011 to 2020
$8.2M
Prevalence and Prognosis of Pulmonary Hypertension in Adults with Sickle CellZIAHL006012 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI TAYLOR, JAMES · 2009 to 2016
$3.5M
Cardiopulmonary Function Assessment and NO Based Therapies for SCD Pts with PAHZIAHL006015 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KATO, GREGORY · 2009 to 2012
$530k
Nitric Oxide for Patients with Sickle Cell Anemia and Pulmonary HypertensionZIAHL006011 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KATO, GREGORY · 2009 to 2012
$360k
Intramural NIH HHS ZIA HL004607Intramural NIH HHS ZIA HL006011Intramural NIH HHS ZIA HL006012Intramural NIH HHS ZIA HL006015Intramural NIH HHS ZIA HL006137Intramural NIH HHS ZID HL006140Intramural NIH HHS ZIE HL006139PHS HHS 1ZIAHL004607PHS HHS 1ZIAHL006011PHS HHS 1ZIAHL006012PHS HHS 1ZIAHL006015PHS HHS 1ZIAHL006137PHS HHS 1ZIDHL006140PHS HHS 1ZIEHL006139
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Vascular ResistanceVentricular RemodelingAdultAnemia, Sickle CellCardiac CatheterizationCardiac OutputCardiac VolumeFemaleHeart RateHumansHypertension, PulmonaryMagnetic Resonance ImagingMaleMiddle AgedSurvival AnalysisVentricular Function, Rightcardiomyopathymagnetic resonance imagingpulmonary hypertensionright ventriclesickle cell disease

Identifiers

PMID26589907
PMCPMC4938326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.