ArticleProceedings of the National Academy of Sciences of the United States of America2015
Laser refrigeration of hydrothermal nanocrystals in physiological media.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Article
- Critical Limitations in Cryogenic Laser Cooling of Solids: Symmetry-Related Fluorescence Trapping and Condensation-Induced Parasitic Heating.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A Thermogenetic Tool Employing Elastin-like Polypeptides for Controlling Programmed Cell Death.ACS nano · 2025Article
- Preparation and Characterization of Uniform and Controlled Silica Encapsulating on Lithium Yttrium Fluoride-Based Upconversion Nanoparticles.Nanomaterials (Basel, Switzerland) · 2024Article
- Luminescence Thermometry Beyond the Biological Realm.ACS nanoscience Au · 2024Review
- Nucleation and Growth of Bipyramidal Yb:LiYFChemistry of materials : a publication of the American Chemical Society · 2023Article
- Understanding and Preventing Photoluminescence Quenching to Achieve Unity Photoluminescence Quantum Yield in Yb:YLF Nanocrystals.ACS applied materials & interfaces · 2023Article
- Heat-Mediated Optical Manipulation.Chemical reviews · 2022Review
- Phonon-assisted up-conversion photoluminescence of quantum dots.Nature communications · 2021Article
- Quantum Point Defects for Solid-State Laser Refrigeration.Advanced materials (Deerfield Beach, Fla.) · 2021Review
- Opto-refrigerative tweezers.Science advances · 2021Article
- Advances and challenges for fluorescence nanothermometry.Nature methods · 2020Review
- Article
- Optical Manipulation of Lanthanide-Doped Nanoparticles: How to Overcome Their Limitations.Frontiers in chemistry · 2020Review
- Optically oriented attachment of nanoscale metal-semiconductor heterostructures in organic solvents via photonic nanosoldering.Nature communications · 2019Article
- Can lasers really refrigerate CdS nanobelts?Nature · 2019Article
- Apparent self-heating of individual upconverting nanoparticle thermometers.Nature communications · 2018Article
- Active Thermal Extraction and Temperature Sensing of Near-field Thermal Radiation.Scientific reports · 2016Article
- Heat pulse excitability of vestibular hair cells and afferent neurons.Journal of neurophysiology · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coherent laser radiation has enabled many scientific and technological breakthroughs including Bose-Einstein condensates, ultrafast spectroscopy, superresolution optical microscopy, photothermal therapy, and long-distance telecommunications. However, it has remained a challenge to refrigerate liquid media (including physiological buffers) during laser illumination due to significant background solvent absorption and the rapid (∼ ps) nonradiative vibrational relaxation of molecular electronic excited states. Here we demonstrate that single-beam laser trapping can be used to induce and quantify the local refrigeration of physiological media by >10 °C following the emission of photoluminescence from upconverting yttrium lithium fluoride (YLF) nanocrystals. A simple, low-cost hydrothermal approach is used to synthesize polycrystalline particles with sizes ranging from <200 nm to >1 μm. A tunable, near-infrared continuous-wave laser is used to optically trap individual YLF crystals with an irradiance on the order of 1 MW/cm(2). Heat is transported out of the crystal lattice (across the solid-liquid interface) by anti-Stokes (blue-shifted) photons following upconversion of Yb(3+) electronic excited states mediated by the absorption of optical phonons. Temperatures are quantified through analysis of the cold Brownian dynamics of individual nanocrystals in an inhomogeneous temperature field via forward light scattering in the back focal plane. The cold Brownian motion (CBM) analysis of individual YLF crystals indicates local cooling by >21 °C below ambient conditions in D2O, suggesting a range of potential future applications including single-molecule biophysics and integrated photonic, electronic, and microfluidic devices.
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