Evidence map›Paper›PMID 26589541›Full record

ArticleDevelopmental cognitive neuroscience2015

Introduction to the special issue: Substance use and the adolescent brain: Developmental impacts, interventions, and longitudinal outcomes.

Monica Luciana, Sarah W Feldstein Ewing

Open access · goldAbstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Monica LucianaDevelopmental Cognitive Neuroscience, Department of Psychology and Center for Neurobehavioral Development, University of Minnesota, Minneapolis, 55455 MN, United States. Electronic address: lucia003@umn.edu.
Sarah W Feldstein EwingDepartment of Psychiatry, Oregon Health & Science University, Portland, OR 97239, United States. Electronic address: feldstei@ohsu.edu.
Oregon Health & Science University · USTwin Cities Orthopedics · US

Funding

Disrupted development of neural connections by alcohol initiation in adolescenceR01AA020033 · NIAAA · UNIVERSITY OF MINNESOTA · PI LUCIANA, MONICA · 2011 to 2015
$2.7M
fMRI and Treatment Response with Binge Drinking AdolescentsR01AA023658 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI FELDSTEIN EWING, SARAH W. · 2015 to 2019
$1.7M
NIAAA NIH HHS AA020033NIAAA NIH HHS AA023658NIAAA NIH HHS R01 AA020033NIAAA NIH HHS R01 AA023658
6 · The paper itself

Abstract

Adolescent substance abuse is a major public health problem, particularly given the negative brain and behavioral consequences that often occur during and following acute intoxication. Negative outcomes appear to be especially pronounced when substance use is initiated in the early adolescent years, perhaps due to neural adaptations that increase risk for substance use disorders into adulthood. Recent models to explain these epidemiological trends have focused on brain-based vulnerabilities to use as well as neurodevelopmental aberrations associated with initiation of use in substance naïve samples or through the description of case-control differences between heavy users and controls. Within this research, adolescent alcohol and marijuana users have shown relative decreases in regional gray matter volumes, substance-specific alterations in white matter volumes, deviations in microstructural integrity in white matter tracts that regulate communication between subcortical areas and higher level regulatory control regions, and deficits in functional connectivity. How these brain anomalies map onto other types of youth risk behavior and later vulnerabilities represent major questions for continued research. This special issue addresses these compelling and timely questions by introducing new methodologies, empirical relationships, and perspectives from major leaders in this field.

Indexed as

Adolescent BehaviorAdolescentAdolescent DevelopmentBrainHumansMagnetic Resonance ImagingSubstance-Related DisordersAdolescentNeuroimagingSubstance use, MRI

Identifiers

PMID26589541
PMCPMC4741096
OpenAlexW1808733944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.