ArticlePLoS neglected tropical diseases2015
Shaking the Tree: Multi-locus Sequence Typing Usurps Current Onchocercid (Filarial Nematode) Phylogeny.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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90 citing papers in PubMed.
- Molecular Detection of Filarioid Nematodes in Bats from the Western Brazilian Amazon.Acta parasitologica · 2026Article
- Onchocercidae (Nematoda: Filarioidea) Infecting Colombian Avian Hosts: Insight From Morphotypes of Microfilariae and Molecular Lineages.Integrative zoology · 2026Article
- Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick-borne filarial nematode transmission.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Polymorphic marker regions support divergence of Mansonella sp. "DEUX" and M. perstans.Parasites & vectors · 2026Article
- In cold blood: screening wild Alaskan moose (Parasitology · 2026Article
- A comprehensive review of Onchocercidae nematodes (Nematoda; Filarioidea) infecting wild ruminant ungulates of North and Central America.International journal for parasitology. Parasites and wildlife · 2026Review
- Molecular and Phylogenetic Characterization ofPathogens (Basel, Switzerland) · 2026Article
- Further Description and First Genetic Characterization of Oswaldofilaria bacillaris (Nematoda: Onchocercidae) Infecting the Pantanal Caiman (Caiman yacare), with Insights into the Phylogeny of Oswaldofilaria.Acta parasitologica · 2026Article
- Molecular Characterization ofJournal of parasitology research · 2026Article
- Uncovering a neglected canine filarioid in Asia: First evidence ofCurrent research in parasitology & vector-borne diseases · 2026Article
- Ghosts of symbionts past: the hidden history of the dynamic association between filarial nematodes and their Wolbachia endosymbionts.G3 (Bethesda, Md.) · 2025Article
- Co-infection ofInternational journal for parasitology. Parasites and wildlife · 2025Article
- Molecular detection of filarioid nematodes (Nematoda: Onchocercidae) in wild mammals from different Brazilian biomes.Parasitology · 2025Article
- First identification and seasonal dynamics of hepatozoon and microfilariae in diploderma swinhonis (squamata: agamidae) from Taiwan.Scientific reports · 2025Article
- Morphological redescription and taxonomic reassignment of Deraiophoronema evansi (Lewis, 1882) Romanovitch 1916 n. comb. (syn: Dipetalonema evansi) (Spirurida: Onchocercidae) from camels.Parasites & vectors · 2025Article
- Natural infection of filarioid nematodes in mosquitoes: An approach to neglected disease xenosurveillance and prevention in intercontinental human transit areas in Darién.PLoS neglected tropical diseases · 2025Article
- A vascular filarial nematode in sika deer (International journal for parasitology. Parasites and wildlife · 2025Article
- Host environment shapes filarial parasite fitness and Wolbachia endosymbionts dynamics.PLoS pathogens · 2025Article
- Unveiling the evolutionary pathways ofParasitology · 2025Article
- A review of filarial nematodes parasitizing tick vectors: unraveling global patterns in species diversity, host associations, and interactions with tick-borne pathogens.Parasites & vectors · 2025Review
30 more citing papers are in PubMed but not listed here.
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14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
During the past twenty years, a number of molecular analyses have been performed to determine the evolutionary relationships of Onchocercidae, a family of filarial nematodes encompassing several species of medical or veterinary importance. However, opportunities for broad taxonomic sampling have been scarce, and analyses were based mainly on 12S rDNA and coxI gene sequences. While being suitable for species differentiation, these mitochondrial genes cannot be used to infer phylogenetic hypotheses at higher taxonomic levels. In the present study, 48 species, representing seven of eight subfamilies within the Onchocercidae, were sampled and sequences of seven gene loci (nuclear and mitochondrial) analysed, resulting in the hitherto largest molecular phylogenetic investigation into this family. Although our data support the current hypothesis that the Oswaldofilariinae, Waltonellinae and Icosiellinae subfamilies separated early from the remaining onchocercids, Setariinae was recovered as a well separated clade. Dirofilaria, Loxodontofilaria and Onchocerca constituted a strongly supported clade despite belonging to different subfamilies (Onchocercinae and Dirofilariinae). Finally, the separation between Splendidofilariinae, Dirofilariinae and Onchocercinae will have to be reconsidered.
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