Evidence map›Paper›PMID 26587369›Full record

ArticleCurrent tropical medicine reports2015

Sphingolipids, Lipid Rafts, and Giardial Encystation: The Show Must Go On.

Tavis L Mendez, Atasi De Chatterjee, Trevor Duarte, Joaquin De Leon, Leobarda Robles-Martinez, Siddhartha Das

Open access · bronzeAbstract read
In one paragraph

Article in Current tropical medicine reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Dual RNA Sequencing Reveals Key Events When DifferentFrontiers in cellular and infection microbiology · 2022
    Article
  5. Characterization of Metronidazole-ResistantFrontiers in microbiology · 2022
    Article
  6. Article
  7. Article
  8. The compact genome ofMicrobial genomics · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Transcriptomic Profiling of High-DensityFrontiers in cellular and infection microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tavis L MendezInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
Atasi De ChatterjeeInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
Trevor DuarteInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
Joaquin De LeonInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
Leobarda Robles-MartinezInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
Siddhartha DasInfectious Disease and Immunology Cluster, The Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968, USA ; Department of Biological Sciences, University of Texas at El Paso, 500 W. University Avenue, El Paso, TX 79968-0519, USA.
The University of Texas at El Paso · US

Funding

TOXICOLOGY PROJECTG12RR008124 · NCRR · UNIVERSITY OF TEXAS EL PASO · PI WALSH, ELIZABETH J · 1992 to 2011
$20.8M
Sphingolipid and Mechanism of Cyst Formation by GiardiaR01AI095667 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI DAS, SIDDHARTHA · 2011 to 2015
$2.1M
NCRR NIH HHS G12 RR008124NIAID NIH HHS R01 AI095667
6 · The paper itself

Abstract

Sphingolipids are sphingosine-based phospholipids, which are present in the plasma and endomembranes of many eukaryotic cells. These lipids are involved in various cellular functions, including cell growth, differentiation, and apoptosis. In addition, sphingolipid and cholesterol-enriched membrane microdomains (also called "lipid rafts") contain a set of proteins and lipids, which take part in the signaling process in response to intra- or extracellular stimuli. Recent findings suggest that sphingolipids, especially glucosylceramide, play a critical role in inducing encystation and maintaining the cyst viability in

Indexed as

CystEncystationGiardiaLipidLipid raftsSphingolipid

Identifiers

PMID26587369
PMCPMC4646163
OpenAlexW874855097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.