ArticleJundishapur journal of microbiology2015
High Recovery Rate of Non-albicans Candida Species Isolated From Burn Patients With Candidemia in Iran.
Article in Jundishapur journal of microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Candidemia in pediatric burn patients: Risk factors and outcomes in a retrospective cohort study.Current medical mycology · 2020Article
- High prevalence of itraconazole resistance amongCurrent medical mycology · 2019Article
- Species distribution and antifungal drug susceptibilities of yeasts isolated from the blood samples of patients with candidemia.Scientific reports · 2019Article
- Molecular Analysis of Resistance and Detection of Non-Wild-Type Strains Using Etest Epidemiological Cutoff Values for Amphotericin B and Echinocandins for Bloodstream Candida Infections from a Tertiary Hospital in Qatar.Antimicrobial agents and chemotherapy · 2018Article
- Catheter-related candidemia and identification of causativeCurrent medical mycology · 2018Article
- Candidemia in Febrile Neutropenic Patients; a Brief Report.Emergency (Tehran, Iran) · 2018Article
- Candidemia in patients with prolonged fever in Kashan, Iran.Current medical mycology · 2016Article
- Article
- In Vitro Activities of Six Antifungal Drugs Against Candida glabrata Isolates: An Emerging Pathogen.Jundishapur journal of microbiology · 2016Article
- Sequence-identification ofAdvanced biomedical research · 2016Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood stream infections (BSIs) are major causes of morbidity and mortality in burn patients. Microorganisms responsible for BSI are generally bacteria; however, Candida spp. are the infection agents in as many as 8% of all cases. Burn wound colonization and infections are generally the first steps to systemic infection. Candidemia in burn patients has been associated with high mortality and a prolonged hospital stay.
objectivesCandidemia in burn patients has been defined as a preterminal event, leading to high morbidity and mortality rates among these patients. The aim of this study was to establish the incidence of candidemia in burn patients in Iran. PATIENTS AND
methodsWe consecutively collected 405 blood samples from 113 burn patients. The yeast isolates were identified to the species level using conventional procedures. In vitro antifungal susceptibility of the Candida isolates to amphotericin B, fluconazole, voriconazole and caspofungin was performed using the Etest.
resultsTwenty-seven samples (6.7%) of the blood cultures from 13 patients (12%) were positive for Candida species. Candida parapsilosis (38%) and C. tropicalis (38%) were the most commonly found Candida species, followed by C. albicans (15%) and C. guilliermondii (15%) in the patients. The incidence of candidemia was significantly correlated with increased duration of hospitalization, increased time of stay in the intensive care unit, and higher mortality. The antifungal susceptibility tests demonstrated that amphotericin B and voriconazole had the lowest minimum inhibitory concentrations (MICs) against Candida spp.
conclusionsNon-albicans Candida should be considered as significant pathogens in burned patients with candidemia.
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