Evidence map›Paper›PMID 26586958›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2015

Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes.

Eduardo Sepúlveda, Rui Poínhos, Miguel Constante, José Pais-Ribeiro, Paula Freitas, Davide Carvalho

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Epidemiology and Burden of Peripheral Artery Disease in People With Type 2 Diabetes: A Systematic Literature Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  4. Article
  5. Article
  6. Health-related quality of life and health utilities in insulin-treated type 2 diabetes: the impact of related comorbidities/complications.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eduardo SepúlvedaFaculty of Psychology and Educational Sciences, University of Porto, Porto, Portugal ; Associação de Prevenção e Apoio à Diabetes, Porto, Portugal.
Rui PoínhosAssociação de Prevenção e Apoio à Diabetes, Porto, Portugal ; Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.
Miguel ConstanteInstitute of Psychiatry, King's College London, London, UK ; Department of Psychiatry, Hospital Beatriz Ângelo, Loures, Portugal.
José Pais-RibeiroFaculty of Psychology and Educational Sciences, University of Porto, Porto, Portugal ; Associação de Prevenção e Apoio à Diabetes, Porto, Portugal.
Paula FreitasDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal ; Faculty of Medicine, University of Porto, Porto, Portugal ; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Davide CarvalhoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal ; Faculty of Medicine, University of Porto, Porto, Portugal ; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Universidade do Porto · PTHospital Beatriz Ângelo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the relationship between health-related quality of life (HRQoL) and the presence or absence of hypertension and diabetes-related chronic complications in type 2 diabetes, and also the association between HRQoL and the number of chronic complications.

methodsOne hundred patients with type 2 diabetes were interviewed. HRQoL was evaluated using the age-adjusted Short-Form 36 dimensions (physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health).

resultsThe mean age of the study population was 62.7±8.7 years; 54.0% were male, and 51.0% were receiving only oral hypoglycemic agents. Chronic complications were related to worse HRQoL in different dimensions: peripheral neuropathy and cardiovascular disease (all, except bodily pain), retinopathy (physical functioning, general health, vitality, and mental health), peripheral arterial disease (physical functioning, role-physical, and general health), and nephropathy (general health and vitality). Hypertension was related to worse general health and vitality. An increased number of chronic complications was associated with worse HRQoL in all dimensions of Short-Form 36 except for the bodily pain dimension.

conclusionThe presence and increased number of diabetes-related chronic complications, and the presence of hypertension were related to worse age-adjusted HRQoL. Peripheral neuropathy and cardiovascular disease were more strongly related to age-adjusted HRQoL.

Indexed as

cardiovascular diseasenephropathyperipheral arterial diseaseperipheral neuropathyretinopathy

Identifiers

PMID26586958
PMCPMC4634825
OpenAlexW2098842387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.