ArticlePlant physiology2016
A G-Box-Like Motif Is Necessary for Transcriptional Regulation by Circadian Pseudo-Response Regulators in Arabidopsis.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 81 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
81 citing papers in PubMed, 156 citations in OpenAlex.
- Unveiling previously undescribed circadian clock regulators and action mechanisms via TurboID-based profiling of the LWD1 interactome inProceedings of the National Academy of Sciences of the United States of America · 2026Article
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- CsPRR7 negatively regulates cold tolerance by repressing CsCBF3 in tea plants.Plant cell reports · 2026Article
- Genome-Wide Characterization and Seasonal-Circadian Expression Analysis of CCT Family Genes inGenes · 2026Article
- The core clock transcription factor TOC1 binds directly to defence gene promoters regulating immunity in Arabidopsis.Communications biology · 2026Article
- A multi-layered regulatory model uncovers the central role of OsPRR37 in coordinating multiple agronomic traits.BMC plant biology · 2025Article
- Temperature compensation of the Arabidopsis circadian clock.Npj biological timing and sleep · 2025Review
- A 65-kb deletion survey identifies a distalProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Transcriptional activation and repression in the plant circadian clock: Revisiting core oscillator feedback loops and output pathways.Plant communications · 2025Review
- Research progress on delayed flowering under short-day condition inFrontiers in plant science · 2025Review
- HOS15-mediated turnover of PRR7 enhances freezing tolerance.The New phytologist · 2024Article
- The overexpression of the switchgrass (Panicum virgatum L.) genes PvTOC1-N or PvLHY-K affects circadian rhythm and hormone metabolism in transgenic Arabidopsis seedlings.Biotechnology for biofuels and bioproducts · 2024Article
- H3K36 methyltransferase GhKMT3;1a and GhKMT3;2a promote flowering in upland cotton.BMC plant biology · 2024Article
- HOS15-mediated turnover of PRR7 enhances freezing tolerance.bioRxiv : the preprint server for biology · 2024Article
- Metabolome profiling and transcriptome analysis unveiling the crucial role of magnesium transport system for magnesium homeostasis in tea plants.Horticulture research · 2024Article
- Petunia PHYTOCHROME INTERACTING FACTOR 4/5 transcriptionally activates key regulators of floral scent.Plant molecular biology · 2024Article
- PIF transcriptional regulators are required for rhythmic stomatal movements.Nature communications · 2024Article
- Complex epistatic interactions between ELF3, PRR9, and PRR7 regulate the circadian clock and plant physiology.Genetics · 2024Article
- TheCells · 2023Review
- A regulatory loop establishes the link between the circadian clock and abscisic acid signaling in rice.Plant physiology · 2023Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PSEUDO-RESPONSE REGULATORs (PRRs) play overlapping and distinct roles in maintaining circadian rhythms and regulating diverse biological processes, including the photoperiodic control of flowering, growth, and abiotic stress responses. PRRs act as transcriptional repressors and associate with chromatin via their conserved C-terminal CCT (CONSTANS, CONSTANS-like, and TIMING OF CAB EXPRESSION 1 [TOC1/PRR1]) domains by a still-poorly understood mechanism. Here, we identified genome-wide targets of PRR9 using chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) and compared them with PRR7, PRR5, and TOC1/PRR1 ChIP-seq data. We found that PRR binding sites are located within genomic regions of low nucleosome occupancy and high DNase I hypersensitivity. Moreover, conserved noncoding regions among Brassicaceae species are enriched around PRR binding sites, indicating that PRRs associate with functionally relevant cis-regulatory regions. The PRRs shared a significant number of binding regions, and our results indicate that they coordinately restrict the expression of target genes to around dawn. A G-box-like motif was overrepresented at PRR binding regions, and we showed that this motif is necessary for mediating transcriptional regulation of CIRCADIAN CLOCK ASSOCIATED 1 and PRR9 by the PRRs. Our results further our understanding of how PRRs target specific promoters and provide an extensive resource for studying circadian regulatory networks in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.