Evidence map›Paper›PMID 26586576›Full record

ArticleScientific reports2015

Resequencing of the common marmoset genome improves genome assemblies and gene-coding sequence analysis.

Kengo Sato, Yoko Kuroki, Wakako Kumita, Asao Fujiyama, Atsushi Toyoda, Jun Kawai, Atsushi Iriki, Erika Sasaki, Hideyuki Okano, Yasubumi Sakakibara

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. A Complete Genome for the Common Marmoset.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Kengo SatoDepartment of Biosciences and Informatics, Keio University, Japan.
Yoko KurokiDepartment of Genome Medicine, National Research Institute for Child Health and Development, NCCHD, Japan.
Wakako KumitaDepartment of Applied Developmental Biology, Central Institute for Experimental Animals, Japan.
Asao FujiyamaPrinciples of Informatics Research Division, National Institute of Informatics, Japan.
Atsushi ToyodaCenter for Information Biology, National Institute of Genetics, Japan.
Jun KawaiPreventive Medicine and Diagnosis Innovation Program, RIEKN, Japan.
Atsushi IrikiLaboratory for Symbolic Cognitive Development, Brain Science Institute RIKEN, Japan.
Erika SasakiDepartment of Applied Developmental Biology, Central Institute for Experimental Animals, Japan.
Hideyuki OkanoDepartment of Physiology, Keio University School of Medicine, Japan.
Yasubumi SakakibaraDepartment of Biosciences and Informatics, Keio University, Japan.
Central Institute for Experimental Animals · JPKeio University · JPRIKEN Center for Brain Science · JPNational Center For Child Health and Development · JPNational Institute of Genetics · JPNational Institute of Informatics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first draft of the common marmoset (Callithrix jacchus) genome was published by the Marmoset Genome Sequencing and Analysis Consortium. The draft was based on whole-genome shotgun sequencing, and the current assembly version is Callithrix_jacches-3.2.1, but there still exist 187,214 undetermined gap regions and supercontigs and relatively short contigs that are unmapped to chromosomes in the draft genome. We performed resequencing and assembly of the genome of common marmoset by deep sequencing with high-throughput sequencing technology. Several different sequence runs using Illumina sequencing platforms were executed, and 181 Gbp of high-quality bases including mate-pairs with long insert lengths of 3, 8, 20, and 40 Kbp were obtained, that is, approximately 60× coverage. The resequencing significantly improved the MGSAC draft genome sequence. The N50 of the contigs, which is a statistical measure used to evaluate assembly quality, doubled. As a result, 51% of the contigs (total length: 299 Mbp) that were unmapped to chromosomes in the MGSAC draft were merged with chromosomal contigs, and the improved genome sequence helped to detect 5,288 new genes that are homologous to human cDNAs and the gaps in 5,187 transcripts of the Ensembl gene annotations were completely filled.

Indexed as

AnimalsCallithrixContig MappingGenomeHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationOpen Reading FramesPrincipal Component AnalysisSequence Analysis, DNA

Identifiers

PMID26586576
PMCPMC4653617
OpenAlexW2300190949

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.