Trial reportJournal of bone and mineral metabolism2016
Relationships between the lean mass index and bone mass and reference values of muscular status in healthy Chinese children and adolescents.
Trial report in Journal of bone and mineral metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sarcopenic Obesity in Children and Adolescents: A Systematic Review.Frontiers in endocrinology · 2022Pooled it
- Sarcopenic Obesity in Children: An Emerging Complication Evidenced by Clinical Data and a Juvenile Mouse Model.Journal of cachexia, sarcopenia and muscle · 2026Article
- Mechanical Load-Capacity Models for Bone in Youth - Analysis of Risk Signatures.Journal of musculoskeletal & neuronal interactions · 2026Article
- Development and validation of a nomogram for osteoporosis based on clinical characteristics in Kunming.Journal of orthopaedic surgery and research · 2025Article
- Sex disparities in body composition trends among elementary school students based on grade.Frontiers in pediatrics · 2025Article
- Updated reference values for BMD and lean mass measured by DXA in Thai children.Journal of bone and mineral metabolism · 2024Article
- Reference ranges for body composition indices by dual energy X-ray absorptiometry from the Bone Mineral Density in Childhood Study Cohort.The American journal of clinical nutrition · 2023Observational
- The relationship between obesity and bone mineral density in children and adolescents: analysis of the National Health and Nutrition Examination Survey.Archives of osteoporosis · 2023Article
- Different associations between waist circumference and bone mineral density stratified by gender, age, and body mass index.BMC musculoskeletal disorders · 2022Article
- Official Position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry-part II (clinical aspects): interpretation, reporting, and special situations.Advances in rheumatology (London, England) · 2022Article
- The Relationship between Body Composition and Bone Mineral Density of Female Workers in A Unit of Tai'an.Computational and mathematical methods in medicine · 2022Article
- Review
- Relationships of sex hormones with muscle mass and muscle strength in male adolescents at different stages of puberty.PloS one · 2021Article
- Article
- Quantification of skeletal muscle mass: sarcopenia as a marker of overall health in children and adults.Pediatric radiology · 2020Review
- Lean mass reference curves in adolescents using dual-energy x-ray absorptiometry (DXA).PloS one · 2020Article
- Development of a Computational Model to Predict Excess Body Fat in Adolescents through Low Cost Variables.International journal of environmental research and public health · 2019Article
- Differences in the relation between bone mineral content and lean body mass according to gender and reproductive status by age ranges.Journal of bone and mineral metabolism · 2019Article
- Observational
- Muscle Mass in Children and Adolescents: Proposed Equations and Reference Values for Assessment.Frontiers in endocrinology · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to analyze the relationships between the lean mass index (LMI) and bone outcomes in Chinese children and adolescents using dual-energy X-ray absorptiometry (DXA) and to establish sex-specific reference percentile curves for the assessment of muscle status. A total of 1541 Chinese children and adolescents between the ages of 5 and 19 years were recruited from southern China. Body composition was measured by DXA (Lunar Prodigy) to acquire total body and total body less head (TBLH) measures. LMI was calculated as the LM (kg) divided by the height in meters squared. Strong sex gaps were observed after age 14 in total body LMI and appendicular LMI (p < 0.001). LM and LMI values continued to increase for boys up to age 14 compared to girls who plateaued after age 12. For each sex group, total body bone mineral content (BMC) and TBLH BMC were highly correlated with total body LMI and appendicular LMI (r = 0.856-0.916 in boys, and r = 0.651-0.804 in girls, p < 0.001). The appendicular LMI was more strongly associated with total body BMC and TBLH BMC than was total body LMI. The correlations between the BMC values and the LM measures were stronger than the fat mass results. We also present sex-specific percentile curves for LM-age and LMI-age relationships, which could be useful for identifying the LM deficits in this population.
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