Evidence map›Paper›PMID 26586203›Full record

ArticleJournal of veterinary internal medicine

Clinical Utility of Diagnostic Laboratory Tests in Dogs with Acute Pancreatitis: A Retrospective Investigation in a Primary Care Hospital.

M Yuki, T Hirano, N Nagata, S Kitano, K Imataka, R Tawada, R Shimada, M Ogawa

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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  8. Article
  9. Advances in the diagnosis of acute pancreatitis in dogs.Journal of veterinary internal medicine · 2021
    Review
  10. Article
  11. Bile duct obstruction associated with pancreatitis in 46 dogs.Journal of veterinary internal medicine · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

M YukiYuki Animal Hospital, Nagoya, Aichi, Japan.
T HiranoYuki Animal Hospital, Nagoya, Aichi, Japan.
N NagataYuki Animal Hospital, Nagoya, Aichi, Japan.
S KitanoYuki Animal Hospital, Nagoya, Aichi, Japan.
K ImatakaYuki Animal Hospital, Nagoya, Aichi, Japan.
R TawadaYuki Animal Hospital, Nagoya, Aichi, Japan.
R ShimadaYuki Animal Hospital, Nagoya, Aichi, Japan.
M OgawaYuki Animal Hospital, Nagoya, Aichi, Japan.
Yuki Animal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pancreatitis (AP) occurs frequently in dogs, but most previous studies examining the diagnosis of AP have used data from secondary care hospitals. HYPOTHESIS/

objectivesThe aim of this study was to investigate the clinical utility of diagnostic laboratory tests in dogs with AP in a primary care hospital. ANIMALS: Sixty-four dogs with clinical signs suggestive of AP diagnosed with nonpancreatic disease (NP) or AP.

methodsMedical records were retrospectively reviewed, including diagnostic laboratory tests considered potentially useful in the diagnosis of AP. The diagnostic accuracy of amylase and FUJI DRI-CHEM lipase (FDC lip) were investigated using receiver operating characteristics (ROC). In addition, we verified whether diagnostic laboratory tests were useful for evaluating duration of hospitalization and as biomarkers for monitoring recovery.

resultsActivities of amylase and FDC lip were significantly higher in the AP group than in the NP group (P = .001, P < .001, respectively). The sensitivity of FDP lip activity for diagnosing AP was 100% (95% confidence interval [CI], 87.7-100%); the specificity was 89.5% (95% CI, 66.9-98.7%). Area under the ROC curve for FDC lip activity was 0.98 (95% CI, 0.93-1). High alanine aminotransferase (ALT) activity was associated with extended duration of hospitalization (P = .04). A significant difference in C-reactive protein (CRP) concentration before and 5 days after treatment was found (P = .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Measurement of FDC lip activity appears useful for diagnosing AP. High ALT activity might be associated with prolonged duration of hospitalization, and CRP might be useful as a biomarker for monitoring recovery from AP.

Indexed as

Acute DiseaseAmylasesAnimalsBiomarkersDog DiseasesDogsFemaleHospitals, AnimalLipaseMalePancreasPancreatitisRetrospective StudiesSensitivity and SpecificityAmylasesBiomarkersLipaseCanineinflammationpancreas

Identifiers

PMID26586203
PMCPMC4913649
OpenAlexW2180595167

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.