ArticleBMC medicine2015
Current tobacco use is associated with higher rates of implant revision and deep infection after total hip or knee arthroplasty: a prospective cohort study.
Article in BMC medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Impact of smoking on the incidence and post-operative complications of total knee arthroplasty: A systematic review and meta-analysis of cohort studies.Bosnian journal of basic medical sciences · 2022Pooled it
- Implementing a hip arthroplasty program in Greenland, the autonomous territory of Denmark: challenges and outcomes.International orthopaedics · 2026Article
- A modified lateral skin incision reduces wound complications and hospital stay in morbidly obese patients undergoing total knee arthroplasty: a propensity-matched cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Nicotine use is Associated With Elevated Risk of Opioid use Disorder Following Total/Hemi Hip Arthroplasty Procedures.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Periprosthetic joint infection after arthroplasty: advances and future prospects.Journal of orthopaedic surgery and research · 2025Review
- What is the Association Between Nontobacco Nicotine Dependence and Postoperative Complications in Total Hip Arthroplasty? A Large Propensity-Matched Cohort Study.Arthroplasty today · 2025Article
- Risk factors and bacterial spectrum postoperative infections after esophageal tumor surgery in patients aged ≥60 years.Frontiers in oncology · 2025Article
- Article
- Robotic arm-assisted versus conventional total knee arthroplasty: comparing complications, costs, and postoperative opioid use in propensity-matched cohorts.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Preoperative Risk Factors for Periprosthetic Joint Infection: A Narrative Review of the Literature.Healthcare (Basel, Switzerland) · 2024Review
- Smoking is associated with higher short-term risk of revision and mortality following primary hip or knee arthroplasty: a cohort study of 272,640 patients from the Dutch Arthroplasty Registry.Acta orthopaedica · 2024Article
- Outpatient Hip and Knee Arthroplasty Can be Safe in Patients With Multiple Medical Comorbidities via Use of Evidence-Based Perioperative Protocols.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024Article
- Smokers have increased risk of soft-tissue complications following primary elective TKA.Archives of orthopaedic and trauma surgery · 2023Article
- Effect of Tobacco Use on Radiolucent Lines in Modern Cementless Total Knee Arthroplasty Tibial Components.Arthroplasty today · 2023Article
- Factfinders for patient safety: Antibiotics for disc access and spinal cord stimulation trials.Interventional pain medicine · 2022Article
- Risk Factors for Periprosthetic Joint Infection after Primary Total Knee Arthroplasty.Journal of clinical medicine · 2022Review
- A practical guide for perioperative smoking cessation.Journal of anesthesia · 2022Review
- Is Prior Hip Arthroscopy Associated With Higher Complication Rates or Prolonged Opioid Claims After Total Hip Arthroplasty? A Matched Cohort Study.Orthopaedic journal of sports medicine · 2022Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTobacco smoking is a risk factor for several adverse post-operative outcomes. We aimed to compare the rates of complications in current tobacco users and non-users who underwent primary total hip arthroplasty (THA) or total knee arthroplasty (TKA).
methodsAll patients who underwent primary THA or TKA at the Mayo Clinic from 2010-2013 were included in the study. Current tobacco use was defined as the use of cigarettes, cigars, pipes, or smokeless tobacco reported at the time of index THA or TKA; current non-users were former users or never users. We used Cox proportional hazards regression to assess the association of current tobacco use status with each post-THA/TKA complication, using hazard ratios and 95% confidence intervals (CI).
resultsTobacco use status was available for 7926 patients (95%) and not available for 446 patients (5%); 565 (7%) were current tobacco users. Compared to non-users, current tobacco users were more likely to be male (p < 0.001), and less likely to be obese (p ≤ 0.008), be older than 60 years, have Charlson score >0 or have undergone TKA rather than THA (p < 0.001 each). The hazard ratios for deep infection (2.37; 95% CI 1.19, 4.72; p = 0.01) and implant revision (1.78; 95% CI 1.01, 3.13; p = 0.04) were higher in current tobacco users than in non-users. No significant differences were noted for periprosthetic fractures or superficial infections.
conclusionsWe noted that current tobacco use was associated with high risk of deep infection and implant revision after primary THA or TKA. Future studies should determine the optimal time for tobacco use cessation before elective surgeries such as THA and TKA to improve short-term and long-term arthroplasty outcomes.
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