Evidence map›Paper›PMID 26585462›Full record

ArticleJournal of ophthalmic inflammation and infection2015

Three-dimensional spectral domain optical coherence tomography and light microscopy of an intravitreal parasite.

Aziz A Khanifar, Michael J Espiritu, Jane S Myung, Grant D Aaker, Audrey N Schuetz, Donald J D'Amico, R V Paul Chan

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Ocular Gnathostomiasis-Update of Earlier Survey.The American journal of tropical medicine and hygiene · 2017
    Article
  3. A case of ophthalmomyiasis interna in the Pacific Northwest.American journal of ophthalmology case reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aziz A KhanifarDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. azizkhanifar@gmail.com.
Michael J EspirituDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. mj.espiritu@gmail.com.
Jane S MyungDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. janesmyung@gmail.com.
Grant D AakerDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. aaker.grant@gmail.com.
Audrey N SchuetzDepartment of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA. ans9112@med.cornell.edu.
Donald J D'AmicoDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. djd2003@med.cornell.edu.
R V Paul ChanDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA. rvpchan@uic.edu.
Cornell University · USUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious imaging modalities play a role in diagnosing parasitic infections of the eye. We describe the spectral domain optical coherence tomography (SD-OCT) findings of an intravitreal parasite with subsequent evaluation by light microscopy.

findingsThis is a case report of a 37-year-old Ecuadorian man who presented with uveitic glaucoma and a new floater in his left eye for 1 week's duration. Full ophthalmic examination revealed an intravitreal parasite. Color fundus photography, fluorescein angiography (FA), ocular ultrasonography (US), and SD-OCT were performed. The parasite was removed via 23-gauge pars plana vitrectomy and sent to pathology for evaluation. Color fundus photography and ocular ultrasonography demonstrated an elongated foreign body within the vitreous above the retina. FA demonstrated minimal vascular changes in the vicinity of the parasite. SD-OCT was utilized to visualize the parasite and to create a three-dimensional (3D) image. The parasite was determined to be most consistent with Gnathostoma spp. by morphologic analysis.

conclusionsThis is the first reported case of SD-OCT of an intravitreal parasite with corresponding evaluation by pathology. SD-OCT allows non-invasive, high-resolution visualization and 3D reconstruction of parasitic anatomy which may help establish tomographic criteria for species identification.

Indexed as

GnathostomaGnathostomiasisOphthalmomyiasisOptical coherence tomographyParasitic infectionRetinal imaging

Identifiers

PMID26585462
PMCPMC4653122
OpenAlexW2173229726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.