Evidence map›Paper›PMID 26585337›Full record

SynthesisEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2016

Value of brain MRI in infective endocarditis: a narrative literature review.

J Champey, P Pavese, H Bouvaist, A Kastler, A Krainik, P Francois

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. [Impact of a dedicated multidisciplinary committee (Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  4. Article
  5. An enigmatic presentation ofClinical case reports · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Current cardiology reports · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Is brain angio-MRI useful in infective endocarditis management?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
  20. Infective endocarditis.Nature reviews. Disease primers · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

J ChampeyMedical Intensive Care Department, CHU de Grenoble, BP 218, 38043, Grenoble Cedex 9, France. JChampey@chu-grenoble.fr.
P PaveseInfectious Diseases Department, CHU de Grenoble, BP 218, 38043, Grenoble Cedex 9, France. PPavese@chu-grenoble.fr.
H BouvaistCardiology Department, CHU Grenoble, Grenoble, France.
A KastlerNeuroradiology Department, CHU Grenoble, Grenoble, France.
A KrainikNeuroradiology Department, CHU Grenoble, Grenoble, France.
P FrancoisPublic Health Department, CHU Grenoble, Grenoble, France.
Centre Hospitalier Universitaire de Grenoble · FRLaboratoire de Biologie Computationnelle et Quantitative · FRLaboratoire de Psychologie et NeuroCognition · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system is frequently involved in patients with infective endocarditis (IE). A systematic review of the literature was realized in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). This study sought to systematically evaluate the published evidence of the contribution of brain magnetic resonance imaging (MRI) in IE. The aim was to identify studies presenting the incidence and type of MRI brain lesions in IE. Fifteen relevant studies were isolated using the Medline, Embase, and Cochrane databases. Most of them were observational studies with a small number of patients. MRI studies demonstrated a wide variety and high frequency of cerebral lesions, around 80 % of which were mostly clinically occult. This review shows MRI's superiority compared to brain computed tomography (CT) for the diagnosis of neurologic complications. Recent developments of sensitive MRI sequences can detect microinfarction and cerebral microhemorrhages. However, the clinical significance of these microhemorrhages, also called cerebral microbleeds (CMBs), remains uncertain. Because some MRI neurological lesions are a distinctive IE feature, they can have a broader involvement in diagnosis and therapeutic decisions. Even if cerebral MRI offers new perspectives for better IE management, there is not enough scientific proof to recommend it in current guidelines. The literature remains incomplete regarding the impact of MRI on concerted decision-making. The long-term prognosis of CMBs has not been evaluated to date and requires further studies. Today, brain MRI can be used on a case-by-case basis based on a clinician's appraisal.

Indexed as

Clinical Decision-MakingAneurysm, InfectedBrainBrain AbscessCerebral HemorrhageEndocarditis, BacterialHumansMagnetic Resonance ImagingMeningitis, BacterialPrognosis

Identifiers

PMID26585337
PMCPMC4724368
OpenAlexW2175508482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.