ArticleAJNR. American journal of neuroradiology2016
Evaluation of Subependymal Gray Matter Heterotopias on Fetal MRI.
Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What brain abnormalities can magnetic resonance imaging detect in foetal and early neonatal spina bifida: a systematic review.Neuroradiology · 2022Pooled it
- Fetal malformations of cortical development: review and clinical guidance.Brain : a journal of neurology · 2025Review
- Review
- Assessment of longitudinal brain development using super-resolution magnetic resonance imaging following fetal surgery for open spina bifida.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2023Article
- Early Diagnosis of Tuberous Sclerosis Complex: Prenatal Diagnosis.AJNR. American journal of neuroradiology · 2023Article
- Value of pre- and postnatal magnetic resonance imaging in the evaluation of congenital central nervous system anomalies.Pediatric radiology · 2022Review
- The Role of Fetal Brain Magnetic Resonance Imaging in Current Fetal Medicine.Journal of the Belgian Society of Radiology · 2022Article
- Cortical spectral matching and shape and volume analysis of the fetal brain pre- and post-fetal surgery for spina bifida: a retrospective study.Neuroradiology · 2021Article
- Fetal magnetic resonance imaging: supratentorial brain malformations.Pediatric radiology · 2020Review
- Imaging of open spinal dysraphisms in the era of prenatal surgery.Pediatric radiology · 2020Review
- Fetal Intraventricular Hemorrhage in Open Neural Tube Defects: Prenatal Imaging Evaluation and Perinatal Outcomes.AJNR. American journal of neuroradiology · 2020Article
- Reliability of MR Imaging-Based Posterior Fossa and Brain Stem Measurements in Open Spinal Dysraphism in the Era of Fetal Surgery.AJNR. American journal of neuroradiology · 2019Article
- Evolution of posterior fossa and brain morphology after in utero repair of open neural tube defects assessed by MRI.European radiology · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSubependymal grey matter heterotopias are seen in a high proportion of children with Chiari II malformation and are potentially clinically relevant. However, despite its growing use, there is little in the literature describing its detection on fetal MRI. Our aim was to evaluate the accuracy in diagnosing subependymal gray matter heterotopias in fetuses with spinal dysraphism on fetal MR imaging. MATERIALS AND
methodsThis study is a retrospective analysis of 203 fetal MRIs performed at a single institution for spinal dysraphism during a 10-year period. Corresponding obstetric sonography, postnatal imaging, and clinical/operative reports were reviewed.
resultsOf the fetal MRIs reviewed, 95 fetuses were included in our analysis; 23.2% (22/95) were suspected of having subependymal gray matter heterotopias on fetal MR imaging prospectively. However, only 50% (11/22) of these cases were confirmed on postnatal brain MR imaging. On postnatal brain MR imaging, 28.4% (27/95) demonstrated imaging findings consistent with subependymal gray matter heterotopia. Only 40.7% (11/27) of these cases were prospectively diagnosed on fetal MR imaging.
conclusionsFetal MR imaging is limited in its ability to identify subependymal gray matter heterotopias in fetuses with spinal dysraphism. It is believed that this limitation relates to a combination of factors, including artifacts from fetal motion, the very small size of fetal neuroanatomy, differences in imaging techniques, and, possibly, irregularity related to denudation of the ependyma/subependyma in the presence of spinal dysraphism and/or stretching of the germinal matrix in ventriculomegaly.
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