ArticleAJNR. American journal of neuroradiology2016
The Cervical Spinal Canal Tapers Differently in Patients with Chiari I with and without Syringomyelia.
Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 12 citations in OpenAlex.
- Associations of Chiari-1 malformation and syringomyelia with osseous cervical spinal canal diameter in the pediatric spine.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Evaluation and Treatment of Patients with Small Posterior Cranial Fossa and Chiari Malformation, Types 0 and 1.Advances and technical standards in neurosurgery · 2024Article
- Spinal subarachnoid space tapering in patients with syringomyelia.The neuroradiology journal · 2019Article
- Cervical spine taper ratios: Normal tolerance limits.The neuroradiology journal · 2018Article
- A Retrospective 2D Morphometric Analysis of Adult Female Chiari Type I Patients with Commonly Reported and Related Conditions.Frontiers in neuroanatomy · 2018Article
- A 3D subject-specific model of the spinal subarachnoid space with anatomically realistic ventral and dorsal spinal cord nerve rootlets.Fluids and barriers of the CNS · 2017Article
- Anatomical features of the cervical spinal canal in Chiari I deformity with presyrinx: A case-control study.The neuroradiology journal · 2017Article
- Cervical spinal canal narrowing in idiopathic syringomyelia.Neuroradiology · 2016Article
- Comment on: "sagittal MRI often overestimates the degree of cerebellar tonsillar ectopia: a potential for misdiagnosis of the Chiari I malformation", by R. Shane Tubbs et al.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe cause of syringomyelia in patients with Chiari I remains uncertain. Cervical spine anatomy modifies CSF velocities, flow patterns, and pressure gradients, which may affect the spinal cord. We tested the hypothesis that cervical spinal anatomy differs between Chiari I patients with and without syringomyelia. MATERIALS AND
methodsWe identified consecutive patients with Chiari I at 3 institutions and divided them into groups with and without syringomyelia. Five readers measured anteroposterior cervical spinal diameters, tonsillar herniation, and syrinx dimensions on cervical MR images. Taper ratios for C1-C7, C1-C4, and C4-C7 spinal segments were calculated by linear least squares fitting to the appropriate spinal canal diameters. Mean taper ratios and tonsillar herniation for groups were compared and tested for statistical significance with a Kruskal-Wallis test. Inter- and intrareader agreement and correlations in the data were measured.
resultsOne hundred fifty patients were included, of which 49 had syringomyelia. C1-C7 taper ratios were smaller and C4-C7 taper ratios greater for patients with syringomyelia than for those without it. C1-C4 taper ratios did not differ significantly between groups. Patients with syringomyelia had, on average, greater tonsillar herniation than those without a syrinx. However, C4-C7 taper ratios were steeper, for all degrees of tonsil herniation, in patients with syringomyelia. Differences among readers did not exceed differences among patient groups.
conclusionsThe tapering of the lower cervical spine may contribute to the development of syringomyelia in patients with Chiari I.
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