Evidence map›Paper›PMID 26584626›Full record

Trial reportRadiation oncology (London, England)2015

Collimator rotation in volumetric modulated arc therapy for craniospinal irradiation and the dose distribution in the beam junction region.

Qilin Li, Wendong Gu, Jinming Mu, Wenming Yin, Min Gao, Juncong Mo, Honglei Pei

Abstract readClinical Trial
In one paragraph

Trial report in Radiation oncology (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Craniospinal irradiation planning and delivery: a comparison between Halcyon Ring Gantry and TrueBeam C Arm LINAC delivery systems.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  4. Article
  5. Article
  6. Evolution of dosimetric treatment planning for pediatric total lymphoid irradiation (TLI): a single-institution experience.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qilin LiDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. forster3602@126.com.
Wendong GuDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. hony0428@126.com.
Jinming MuDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. mjm_f@hotmail.com.
Wenming YinDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. Ywenming19@163.com.
Min GaoDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. gaominwzgl_2007@126.com.
Juncong MoDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. acmolin@sina.com.
Honglei PeiDepartment of Radiation Oncology, The Third Affiliated Hospital of Soochow University, The First People's Hospital of Changzhou City, 185 Ju Qian Jie, Changzhou City, 213003, Jiangsu Province, China. Hongleipei@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the role of beam collimator rotation in Volumetric Modulated Arc Therapy (VMAT) for craniospinal irradiation (CSI), and the impact on dose distribution in the beam junctions.

methodsSix adult patients were selected for the study. Six VMAT plans with different collimator angles were generated for each patient. The patients were treated in supine position with two beam isocenters. The plans were evaluated by analysis of Dose-Volume Histogram (DVHs) data for planning target volume (PTV) and organs at risk (OAR), and conformity index (CI) and homogeneity index (HI) for the target. Dose distributions in the beam junctions were examined carefully and experimentally validated in phantom, with measurement using an ion chamber array and film.

resultsThe mean values of HI and CI for the plans with different beam collimator angles were not significantly different. The numbers of segments, monitor units (MUs) and the delivery time of the plans with 45° beam collimator were obviously higher than those in plans with other beam collimator angles. When collimator angle for both sets of beams were set at 0°, there was a 1 mm low dose gap measured in the junction region.

conclusionsBy setting the collimator angle to 45°, only two isocenters were needed for the treatment of a target with the length up to 90 cm. The HI and CI of the plans were almost the same, regardless if the collimator angles were at 0°. The collimator angles for at least one set of beams should be off 0° in order to avoid a dose gap in the beam junction region.

Indexed as

AdultCraniospinal IrradiationFemaleHumansMaleMiddle AgedOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRotation

Identifiers

PMID26584626
PMCPMC4653929

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.