Evidence map›Paper›PMID 26584575›Full record

ArticleEuropean child & adolescent psychiatry2016

The objectivity of the Autism Diagnostic Observation Schedule (ADOS) in naturalistic clinical settings.

Eric Zander, Charlotte Willfors, Steve Berggren, Nora Choque-Olsson, Christina Coco, Anna Elmund, Åsa Hedfors Moretti, Anette Holm, Ida Jifält, Renata Kosieradzki and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Detecting autism from picture book narratives using deep neural utterance embeddings.International journal of language & communication disorders · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. CLEAR Autism Diagnostic Evaluation (CADE): Evaluation of Reliability and Validity.Journal of developmental and physical disabilities · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eric ZanderPediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden. eric.zander@ki.se.ORCID http://orcid.org/0000-0002-2267-5813
Charlotte WillforsPediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Steve BerggrenPediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Nora Choque-OlssonPediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Christina CocoPediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden.
Anna ElmundPRIMA Child and Adolescent Psychiatry, Stockholm, Sweden.
Åsa Hedfors MorettiBUP Sollentuna, Child and Adolescent Psychiatry, Stockholm County Council, Sollentuna, Sweden.
Anette HolmAstrid Lindgrens Children's Hospital, Karolinska University Hospital Solna, Stockholm County Council, Solna, Sweden.
Ida JifältAstrid Lindgrens Children's Hospital, Karolinska University Hospital Huddinge, Stockholm County Council, Huddinge, Sweden.
Renata KosieradzkiBUP Malmö, Child and Adolescent Psychiatry, Region Skåne, Malmö, Sweden.
Jenny LinderSödra Älvsborg Hospital (SÄS), Child and Adolescent Psychiatry, Region Västra Götaland, Borås, Sweden.
Viviann NordinNeuropediatric Unit, Sachs' Children and Youth Hospital, Stockholm County Council, Stockholm, Sweden.
Karin OlafsdottirBUP Lund, Child and Adolescent Psychiatry, Region Skåne, Lund, Sweden.
Lina PoltragoPRIMA Child and Adolescent Psychiatry, Stockholm, Sweden.
Sven BöltePediatric Neuropsychiatry Unit, Department of Women's and Children's Health, Center of Neurodevelopmental Disorders (KIND), Karolinska Institutet, Gävlegatan 22B, 113 30, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Autism Diagnostic Observation Schedule (ADOS) is a first-choice diagnostic tool in autism spectrum disorder (ASD). Excellent interpersonal objectivity (interrater reliability) has been demonstrated for the ADOS under optimal conditions, i.e., within groups of highly trained "research reliable" examiners in research setting. We investigated the spontaneous interrater reliability among clinically trained ADOS users across multiple sites in clinical routine. Forty videotaped administrations of the ADOS modules 1-4 were rated by five different raters each from a pool of in total 15 raters affiliated to 13 different clinical sites. G(q,k) coefficients (analogous to intraclass correlations), kappas (ĸ) and percent agreement (PA) were calculated. The median interrater reliability for items across the four modules was G(q,k) = .74-.83, with the single ADOS items ranging from .23 to .94. G(q,k) for total scores was .85-.92. For diagnostic classification (ASD/non-spectrum), PA was 64-82 % and Fleiss' ĸ .19-.55. Objectivity was lower for pervasive developmental disorder not otherwise specified and non-spectrum diagnoses as compared to autism. Interrater reliabilities of the ADOS items and domain totals among clinical users across multiple sites were in the same range as previously reported for research reliable users, while the one for diagnostic classification was lower. Differences in sample characteristics, rater skills and statistics compared with previous studies are discussed. Findings endorse the objectivity of the ADOS in naturalistic clinical settings, but also pinpoint its limitations and the need and value of adequate and continuous rater training.

Indexed as

Autism Spectrum DisorderChildChild, PreschoolFemaleHumansMalePsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsAutism spectrum disorderDiagnostic instrumentInterrater reliability

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.