ArticleBMC infectious diseases2015
The estimated incidence of pertussis in people aged 50 years old in the United States, 2006-2010.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Epidemiology of pertussis among adolescents, adults, and older adults in selected countries of Latin American: a systematic review.Human vaccines & immunotherapeutics · 2021Pooled it
- Cost-Effectiveness of the 4 Pillars Practice Transformation Program to Improve Vaccination of Adults Aged 65 and Older.Journal of the American Geriatrics Society · 2017Trial
- Whooping cough hospitalisations among patients with chronic conditions: a retrospective analysis of incidence and costs, France, 2008 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- [Potential impact of adjusting immunization procedure for diphtheria-tetanus-pertussis vaccine on pertussis in clinical practice].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Review
- Country-Specific Data and Priorities for Pertussis in Latin America: Recent Findings From the Global Pertussis Initiative.Open forum infectious diseases · 2025Review
- Review
- Estimating the pertussis burden in adolescents and adults in the United States between 2007 and 2019.Human vaccines & immunotherapeutics · 2023Article
- Assessing the Underestimation of Adult Pertussis Disease in Five Latin American Countries.Infectious diseases and therapy · 2023Article
- Assessment of Pertussis Underreporting in Italy.Journal of clinical medicine · 2023Article
- Sero-Epidemiological Study ofVaccines · 2022Article
- Pertussis prevalence among adult patients with acute cough.Turkish journal of medical sciences · 2022Article
- Angioedema as a predominant symptom ofBMJ case reports · 2021Article
- Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis.Human vaccines & immunotherapeutics · 2021Article
- Impact of population aging on the burden of vaccine-preventable diseases among older adults in the United States.Human vaccines & immunotherapeutics · 2021Article
- Cost-effectiveness of increasing vaccination in high-risk adults aged 18-64 Years: a model-based decision analysis.BMC infectious diseases · 2018Article
- Cost effectiveness of a practice-based intervention to improve vaccination rates in adults less than 65-years-old.Human vaccines & immunotherapeutics · 2017Article
- Estimated incidence of pertussis in people aged <50 years in the United States.Human vaccines & immunotherapeutics · 2016Article
- Erratum to: The estimated incidence of pertussis in people aged 50 years old or older in the United States, 2006-2010.BMC infectious diseases · 2016Article
- Article
- Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions.Expert review of vaccinesReview
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPertussis is believed to be widely underreported and under-recognized, particularly among adults. The aim of this study was to estimate the incidence of private practitioner-attended cough illness that could be attributed to Bordetella pertussis in adults aged ≥50 years in the US.
methodsMultiple linear regressions were employed to estimate the overall incidence of pertussis. Data were extracted from IMS' private practice database of longitudinal, patient-level claims and IMS' commercial laboratory database during 4/1/2006-12/31/2010. Patients were ≥50 years old and had ≥1 ICD-9-CM claim for cough illness relating to pertussis, cough, or acute bronchitis. Pertussis positive laboratory tests, seasonal and secular variables were used for estimating the B. pertussis attributable fraction of cough illness.
resultsDuring the study period, there were 20.7 million cases of cough illness among people aged 50-64 and 27.5 million cases among those ≥65; of which the model attributed 2.5 and 1.7 %, respectively, to B. pertussis. The estimated incidences of cough illness attributed to B. pertussis during the study period were on average 202 and 257/100,000 among people aged 50-64 and ≥65 years, respectively, and increased over the years in both age groups. Depending on the year, estimated pertussis incidences were 42 to 105 times higher than medically attended ones in the same database.
conclusionsThese findings indicate that the B. pertussis disease incidence in adults aged ≥50 years is significantly higher than generally estimated. Additional research regarding pertussis reporting and diagnosis in the adult populations is needed to validate these findings.
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