ReviewObesity facts2015
Metabolic Mechanisms in Obesity and Type 2 Diabetes: Insights from Bariatric/Metabolic Surgery.
Review in Obesity facts, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Factors associated with resolution of type-2 diabetes mellitus after sleeve gastrectomy in obese adults.Scientific reports · 2021Trial
- Endoscopically Created Dual-Path Intestinal Diversion Using an Incision-Less Anastomosis System in Obese Subjects: 3-Year Results of Nutrition Observation.Physiological research · 2025Article
- Prioritising patients for publicly funded bariatric surgery in Queensland, Australia.International journal of obesity (2005) · 2024Article
- Unraveling the epigenetic fabric of type 2 diabetes mellitus: pathogenic mechanisms and therapeutic implications.Frontiers in endocrinology · 2024Review
- Research progress on the relationship between bile acid metabolism and type 2 diabetes mellitus.Diabetology & metabolic syndrome · 2023Review
- Diabetic Markers, Five Years after Bariatric Surgery.Middle East journal of digestive diseases · 2023Article
- Cost-Effectiveness of Bariatric Surgery in Tunisia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Bariatric surgery and calcifediol treatment, Gordian knot of severe-obesity-related comorbidities treatment.Frontiers in endocrinology · 2023Article
- Health outcomes of patients with type 2 diabetes following bariatric surgery: Results from a publicly funded initiative.PloS one · 2023Article
- Hepatokines Fetuin-A and Fetuin-B status in obese Saudi patient with diabetes mellitus type 2.American journal of translational research · 2022Article
- Impact of Weight Loss on the Severity of Albuminuria in Obese Diabetic Patients Undergoing Laparoscopic Sleeve Gastrectomy and One-Anastomosis Gastric Bypass.International journal of general medicine · 2022Article
- Bariatric surgery for the management of type 2 diabetes mellitus-current trends and challenges: a review article.American journal of translational research · 2022Review
- Obesity-Related Metabolic Dysfunction in Dairy Cows and Horses: Comparison to Human Metabolic Syndrome.Life (Basel, Switzerland) · 2021Review
- Sweet taste and obesity.European journal of internal medicine · 2021Review
- Current progress in metabolomics of gestational diabetes mellitus.World journal of diabetes · 2021Review
- Nonalcoholic Fatty Liver Disease (NAFLD) as Model of Gut-Liver Axis Interaction: From Pathophysiology to Potential Target of Treatment for Personalized Therapy.International journal of molecular sciences · 2021Review
- Article
- Targeting the G protein-coupled estrogen receptor (GPER) in obesity and diabetes.Endocrine and metabolic science · 2021Article
- Detection of genetic variation and activity analysis of the promoter region of the cattle tRNA-modified geneArchives animal breeding · 2021Article
- Risk Factors Screening for Gestational Diabetes Mellitus Heterogeneity in Chinese Pregnant Women: A Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and the related diabetes epidemics represent a real concern worldwide. Bariatric/metabolic surgery emerged in last years as a valuable therapeutic option for obesity and related diseases, including type 2 diabetes mellitus (T2DM). The complicated network of mechanisms involved in obesity and T2DM have not completely defined yet. There is still a debate on which would be the first metabolic defect leading to metabolic deterioration: insulin resistance or hyperinsulinemia? Insight into the metabolic effects of bariatric/metabolic surgery has revealed that, beyond weight loss and food restriction, other mechanisms can be activated by the rearrangements of the gastrointestinal tract, such as the incretinic/anti-incretinic system, changes in bile acid composition and flow, and modifications of gut microbiota; all of them possibly involved in the remission of T2DM. The complete elucidation of these mechanisms will lead to a better understanding of the pathogenesis of this disease. Our aim was to review some of the metabolic mechanisms involved in the development of T2DM in obese patients as well as in the remission of this condition in patients submitted to bariatric/metabolic surgery.
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