ArticleJournal of occupational and environmental hygiene2015
Aggregate Exposure and Cumulative Risk Assessment--Integrating Occupational and Non-occupational Risk Factors.
Article in Journal of occupational and environmental hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Review of human health exposure assessment frameworks in the United States and development of a unified framework for exposure assessment practitioners.Frontiers in public health · 2026Review
- A detailed methodology for estimating health-related hazards of workplace exposure to indoor formaldehyde vapours.MethodsX · 2024Article
- Progress and recommendations of developing occupational exposure limits for noise-A systematic review.Heliyon · 2024Review
- Expanding the Focus of Occupational Safety and Health: Lessons from a Series of Linked Scientific Meetings.International journal of environmental research and public health · 2022Review
- Thyroid Cancer Diagnostics Related to Occupational and Environmental Risk Factors: An Integrated Risk Assessment Approach.Diagnostics (Basel, Switzerland) · 2022Review
- Pilot study and cumulative risk framework to advance long-haul driver health.Journal of healthy eating and active living · 2022Article
- Cumulative Risks from Stressor Exposures and Personal Risk Factors in the Workplace: Examples from a Scoping Review.International journal of environmental research and public health · 2021Article
- Risk of cardiovascular disease is driven by different combinations of environmental, medical and behavioral factors: Building a conceptual model for cumulative risk assessment.Human and ecological risk assessment : HERA · 2021Article
- Evolving Science and Practice of Risk Assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2021Article
- A Cumulative Risk Perspective for Occupational Health and Safety (OHS) Professionals.International journal of environmental research and public health · 2020Article
- Article
- Use of an Exposome Approach to Understand the Effects of Exposures From the Natural, Built, and Social Environments on Cardio-Vascular Disease Onset, Progression, and Outcomes.Frontiers in public health · 2020Review
- Toward an Expanded Focus for Occupational Safety and Health: A Commentary.International journal of environmental research and public health · 2019Review
- Development and implementation of evidence-based laboratory safety management tools for a public health laboratory.Safety science · 2019Article
- Implications of applying cumulative risk assessment to the workplace.Environment international · 2018Review
- Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting.Mycotoxin research · 2018Article
- Framework for Considering Productive Aging and Work.Journal of occupational and environmental medicine · 2018Review
- Research on Occupational Safety, Health Management and Risk Control Technology in Coal Mines.International journal of environmental research and public health · 2018Article
- A Case Study Application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) Frameworks to Facilitate the Integration of Human Health and Ecological End Points for Cumulative Risk Assessment (CRA).Environmental science & technology · 2018Article
- An Overview of Literature Topics Related to Current Concepts, Methods, Tools, and Applications for Cumulative Risk Assessment (2007-2016).International journal of environmental research and public health · 2017Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Occupational exposure limits have traditionally focused on preventing morbidity and mortality arising from inhalation exposures to individual chemical stressors in the workplace. While central to occupational risk assessment, occupational exposure limits have limited application as a refined disease prevention tool because they do not account for all of the complexities of the work and non-occupational environments and are based on varying health endpoints. To be of greater utility, occupational exposure limits and other risk management tools could integrate broader consideration of risks from multiple exposure pathways and routes (aggregate risk) as well as the combined risk from exposure to both chemical and non-chemical stressors, within and beyond the workplace, including the possibility that such exposures may cause interactions or modify the toxic effects observed (cumulative risk). Although still at a rudimentary stage in many cases, a variety of methods and tools have been developed or are being used in allied risk assessment fields to incorporate such considerations in the risk assessment process. These approaches, which are collectively referred to as cumulative risk assessment, have potential to be adapted or modified for occupational scenarios and provide a tangible path forward for occupational risk assessment. Accounting for complex exposures in the workplace and the broader risks faced by the individual also requires a more complete consideration of the composite effects of occupational and non-occupational risk factors to fully assess and manage worker health problems. Barriers to integrating these different factors remain, but new and ongoing community-based and worker health-related initiatives may provide mechanisms for identifying and integrating risk from aggregate exposures and cumulative risks from all relevant sources, be they occupational or non-occupational.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.