Evidence map›Paper›PMID 26583503›Full record

ArticleClinical and translational gastroenterology2015

Development of Advanced Imaging Criteria for the Endoscopic Identification of Inflammatory Polyps.

Daniel A Sussman, Jodie A Barkin, Aileen M Martin, Tanya Varma, Jennifer Clarke, Maria A Quintero, Heather B Barkin, Amar R Deshpande, Jamie S Barkin, Maria T Abreu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical and translational gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01557387 (Real-time Diagnosis of Pseudopolyps During Colonoscopy Using Noninvasive Advanced Endoscopic Techniques - a Prospective Study), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01557387 completednot on this map

Real-time Diagnosis of Pseudopolyps During Colonoscopy Using Noninvasive Advanced Endoscopic Techniques - a Prospective Study

TypeobservationalSponsorUniversity of MiamiRan2011 to 2013Enrolled75ConditionsPseudopolyp, Inflammatory Bowel DiseaseArmsEndoscopic techniques
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Daniel A SussmanDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Jodie A BarkinDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Aileen M MartinDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Tanya VarmaDepartment of Pathology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Jennifer ClarkeDepartment of Food Science and Technology, Department of Statistics, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Maria A QuinteroDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Heather B BarkinUniversity of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Amar R DeshpandeDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Jamie S BarkinDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
Maria T AbreuDepartment of Medicine, Division of Gastroenterology, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida, USA.
University of Miami · USHealth First · USUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInflammatory polyps (IPs) are frequently encountered at colonoscopy in inflammatory bowel disease (IBD) patients and are associated with an increased risk of colon cancer. The aim of this prospective endoscopic image review and analysis was to describe endoscopic features of IPs in IBD patients at surveillance colonoscopy and determine the ability to endoscopically discern IPs from other colon polyps using high-definition white light (WL), narrow band imaging with magnification (NBI), and chromoendoscopy (CE).

methodsDigital images of IPs using WL, NBI, and CE were reviewed by four attending gastroenterologists using a two-round modified Delphi method. The ability to endoscopically discern IPs from other colon polyps was determined among groups of gastroenterology fellows and attendings. IPs were classified by gross appearance, contour, surface pattern, pit pattern, and appearance of surrounding mucosa in IPs, as well as accuracy of diagnosis.

resultsFeatures characteristic of IPs included a fibrinous cap, surface friability and ulceration, an appendage-like appearance, the halo sign with CE, and a clustering of a multiplicity of IPs. The overall diagnostic accuracy for IP identification was 63% for WL, 42% for NBI, and 64% for CE. High degrees of histologic inflammation significantly improved the accuracy of diagnosis of IP with WL and CE, whereas the use of NBI significantly impaired IP accuracy.

conclusionsThe overall diagnostic accuracy when applying these criteria to clinical images was modest, with incremental benefit with addition of CE to WL. CE showed promise predicting IP histology in actively inflamed tissue. Institutional Review Board approval was obtained. ClinicalTrials.gov Identifier: NCT01557387.

Identifiers

PMID26583503
PMCPMC4816089
OpenAlexW2418141975

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.