Evidence map›Paper›PMID 26583098›Full record

ArticleBioMed research international2015

The Relevance of the High Frequency Audiometry in Tinnitus Patients with Normal Hearing in Conventional Pure-Tone Audiometry.

Veronika Vielsmeier, Astrid Lehner, Jürgen Strutz, Thomas Steffens, Peter M Kreuzer, Martin Schecklmann, Michael Landgrebe, Berthold Langguth, Tobias Kleinjung

Registry-linked trialAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04862572 (Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04862572 nacompletednot on this mapstarted 2021, after this paper: background citation

Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss: Is There a Maladaptive Signature of Auditory Cortex GABA Loss and Dysconnectivity?

TypeinterventionalSponsorUniversity of NottinghamRan2021 to 2022Enrolled76ConditionsTinnitus, Hearing LossArmsMRI scanning
3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Current State of Tinnitus Diagnosis and Treatment: a Multidisciplinary Expert Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  9. Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Veronika VielsmeierDepartment of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany.
Astrid LehnerDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.
Jürgen StrutzDepartment of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany.
Thomas SteffensDepartment of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany.
Peter M KreuzerDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.
Martin SchecklmannDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.
Michael LandgrebeDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany ; Clinic Lech-Mangfall, 83734 Agatharied, Germany.
Berthold LangguthDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.
Tobias KleinjungDepartment of Otorhinolaryngology, University of Regensburg, 93053 Regensburg, Germany ; Department of Otorhinolaryngology, University of Zurich, 8091 Zürich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe majority of tinnitus patients suffer from hearing loss. But a subgroup of tinnitus patients show normal hearing thresholds in the conventional pure-tone audiometry (125 Hz-8 kHz). Here we explored whether the results of the high frequency audiometry (>8 kHz) provide relevant additional information in tinnitus patients with normal conventional audiometry by comparing those with normal and pathological high frequency audiometry with respect to their demographic and clinical characteristics. SUBJECTS AND

methodsFrom the database of the Tinnitus Clinic at Regensburg we identified 75 patients with normal hearing thresholds in the conventional pure-tone audiometry. We contrasted these patients with normal and pathological high-frequency audiogram and compared them with respect to gender, age, tinnitus severity, pitch, laterality and duration, comorbid symptoms and triggers for tinnitus onset.

resultsPatients with pathological high frequency audiometry were significantly older and had higher scores on the tinnitus questionnaires in comparison to patients with normal high frequency audiometry. Furthermore, there was an association of high frequency audiometry with the laterality of tinnitus.

conclusionIn tinnitus patients with normal pure-tone audiometry the high frequency audiometry provides useful additional information. The association between tinnitus laterality and asymmetry of the high frequency audiometry suggests a potential causal role for the high frequency hearing loss in tinnitus etiopathogenesis.

Indexed as

Audiometry, Pure-ToneAdultAuditory ThresholdFemaleHearing LossHumansMaleMiddle AgedSurveys and QuestionnairesTinnitus

Identifiers

PMID26583098
PMCPMC4637018

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.