Evidence map›Paper›PMID 26583061›Full record

ArticleOxidative medicine and cellular longevity2015

Effects of Exercise Intensity on Postexercise Endothelial Function and Oxidative Stress.

Conor McClean, Ryan A Harris, Malcolm Brown, John C Brown, Gareth W Davison

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Conor McCleanSport and Exercise Sciences Research Institute, Ulster University, Jordanstown, County Antrim BT37 0QB, UK.
Ryan A HarrisSport and Exercise Sciences Research Institute, Ulster University, Jordanstown, County Antrim BT37 0QB, UK ; Division of Clinical & Translational Sciences, Georgia Prevention Center, Georgia Regents University, 1120 15th Street HS-1707, Augusta, GA 30912, USA.
Malcolm BrownSport and Exercise Sciences Research Institute, Ulster University, Jordanstown, County Antrim BT37 0QB, UK.
John C BrownSport and Exercise Sciences Research Institute, Ulster University, Jordanstown, County Antrim BT37 0QB, UK.
Gareth W DavisonSport and Exercise Sciences Research Institute, Ulster University, Jordanstown, County Antrim BT37 0QB, UK.
University of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo measure endothelial function and oxidative stress immediately, 90 minutes, and three hours after exercise of varying intensities.

methodsSixteen apparently healthy men completed three exercise bouts of treadmill running for 30 minutes at 55% V̇O(2max) (mild); 20 minutes at 75% V̇O(2max) (moderate); or 5 minutes at 100% V̇O(2max) (maximal) in random order. Brachial artery flow-mediated dilation (FMD) was assessed with venous blood samples drawn for measurement of endothelin-1 (ET-1), lipid hydroperoxides (LOOHs), and lipid soluble antioxidants.

resultsLOOH increased immediately following moderate exercise (P < 0.05). ET-1 was higher immediately after exercise and 3 hours after exercise in the mild trial compared to maximal one (P < 0.05). Transient decreases were detected for ΔFMD/Shear(AUC) from baseline following maximal exercise, but it normalised at 3 hours after exercise (P < 0.05). Shear rate was higher immediately after exercise in the maximal trial compared to mild exercise (P < 0.05). No changes in baseline diameter, peak diameter, absolute change in diameter, or FMD were observed following any of the exercise trials (P > 0.05).

conclusionsAcute exercise at different intensities elicits varied effects on oxidative stress, shear rate, and ET-1 that do not appear to mediate changes in endothelial function measured by FMD.

Indexed as

ExerciseOxidative StressAdultBlood PressureBrachial ArteryEndothelin-1Endothelium, VascularEnzyme-Linked Immunosorbent AssayForced Expiratory VolumeHumansLipid PeroxidesMaleSpectrophotometry, UltravioletEndothelin-1Lipid Peroxides

Identifiers

PMID26583061
PMCPMC4637109
OpenAlexW2145942928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.