ArticleFrontiers in genetics2015
Classifying aging as a disease in the context of ICD-11.
Article in Frontiers in genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Targeting Gli1Stem cell reviews and reports · 2026Review
- A Multimodal Framework for Organ- and Cell-Resolved Biological Aging and Longevity Intervention Discovery.medRxiv : the preprint server for health sciences · 2026Article
- Aging is not a disease: an evolutionary and comparative biological reappraisal.Biogerontology · 2026Review
- Muscle Mass Reference Values of Greek Adult Population: A Cross-Sectional Study for Sarcopenia Definition in Greece.Journal of musculoskeletal & neuronal interactions · 2025Observational
- Ovarian aging: a missing diagnosis in reproductive medicine.Nature medicine · 2025Article
- R4Alz-R: a cutting-edge tool for spotting the very first and subtle signs of aging-related cognitive impairment with high accuracy.GeroScience · 2025Article
- How Were the Elderly RA Patients Doing Over the Past Year?-A Post Hoc Analysis for Telephone Based Following Up to RA Patients in Zunyi China.Journal of inflammation research · 2024Article
- Double-Bind of Recruitment of Older Adults Into Studies of Successful Aging via Assistive Information and Communication Technologies: Mapping Review.JMIR aging · 2022Review
- The landscape of aging.Science China. Life sciences · 2022Review
- Killing Kira, Letting Tom Go?-An Empirical Study on Intuitions Regarding End-of-Life Decisions in Companion Animals and Humans.Animals : an open access journal from MDPI · 2022Article
- Nintedanib induces senolytic effect via STAT3 inhibition.Cell death & disease · 2022Article
- Making Europe health literate: including older adults in sparsely populated Arctic areas.BMC public health · 2022Article
- An essay on the nominal vs. real definitions of aging.Biogerontology · 2021Article
- Article
- Aging, hormones and receptors.Physiological research · 2020Review
- Article
- Review
- The Science Behind NMN-A Stable, Reliable NAD+Activator and Anti-Aging Molecule.Integrative medicine (Encinitas, Calif.) · 2020Article
- mTOR and Aging: An Old Fashioned Dress.International journal of molecular sciences · 2019Review
- Integrating functional ageing into daily clinical practice.Journal of frailty, sarcopenia and falls · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is a complex continuous multifactorial process leading to loss of function and crystalizing into the many age-related diseases. Here, we explore the arguments for classifying aging as a disease in the context of the upcoming World Health Organization's 11th International Statistical Classification of Diseases and Related Health Problems (ICD-11), expected to be finalized in 2018. We hypothesize that classifying aging as a disease with a "non-garbage" set of codes will result in new approaches and business models for addressing aging as a treatable condition, which will lead to both economic and healthcare benefits for all stakeholders. Actionable classification of aging as a disease may lead to more efficient allocation of resources by enabling funding bodies and other stakeholders to use quality-adjusted life years (QALYs) and healthy-years equivalent (HYE) as metrics when evaluating both research and clinical programs. We propose forming a Task Force to interface the WHO in order to develop a multidisciplinary framework for classifying aging as a disease with multiple disease codes facilitating for therapeutic interventions and preventative strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.