ArticleFrontiers in plant science2015
Transcriptome analysis reveals regulatory networks underlying differential susceptibility to Botrytis cinerea in response to nitrogen availability in Solanum lycopersicum.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 59 citations in OpenAlex.
- Bacillus-mediated transcriptional and metabolic reprogramming elicits defense priming in Coptis chinensis roots.Scientific reports · 2026Article
- Aesculetin-mediated recruitment of denitrifying microbiota by resistant rapeseed suppresses Plasmodiophora brassicae via nitrate depletion.The ISME journal · 2026Article
- PME10 Is a Pectin Methylesterase Driving PME Activity and Immunity Against Botrytis cinerea in Grapevine (Vitis vinifera L.).Plant biotechnology journal · 2025Article
- Morphological and Transcriptomic Analyses Provide New Insights into Linseed (Plants (Basel, Switzerland) · 2025Article
- Salicylic acid accumulation: emerging molecular players and novel perspectives on plant development and nutrition.Journal of experimental botany · 2025Review
- Article
- Microbe-Friendly Plants Enable Beneficial Interactions with Soil Rhizosphere Bacteria by Lowering Their Defense Responses.Plants (Basel, Switzerland) · 2024Article
- Modelling metabolic fluxes of tomato stems reveals that nitrogen shapes central metabolism for defence against Botrytis cinerea.Journal of experimental botany · 2024Article
- Nitrogen Deficiency Enhances Eggplant Defense against Western Flower Thrips via the Induction of the Jasmonate Pathway.Plants (Basel, Switzerland) · 2024Article
- Unraveling the Molecular Mechanisms of Tomatoes' Defense againstPlants (Basel, Switzerland) · 2023Article
- Nitrogen use efficiency-a key to enhance crop productivity under a changing climate.Frontiers in plant science · 2023Review
- Article
- Responses of Bunias orientalis to Short-term Fungal Infection and Insect Herbivory are Independent of Nutrient Supply.Journal of chemical ecology · 2022Article
- TOR inhibition primes immunity and pathogen resistance in tomato in a salicylic acid-dependent manner.Molecular plant pathology · 2022Article
- Transcriptome analysis of tea (Frontiers in plant science · 2022Article
- Long-term nitrogen enrichment mediates the effects of nitrogen supply and co-inoculation on a viral pathogen.Ecology and evolution · 2022Article
- High throughput sequencing unravels tomato-pathogen interactions towards a sustainable plant breeding.Horticulture research · 2021Review
- Method for the Production and Purification of Plant Immuno-Active Xylanase fromInternational journal of molecular sciences · 2021Article
- Every cloud has a silver lining: how abiotic stresses affect gene expression in plant-pathogen interactions.Journal of experimental botany · 2021Review
- Regulation of sugar metabolism genes in the nitrogen-dependent susceptibility of tomato stems to Botrytis cinerea.Annals of botany · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen (N) is one of the main limiting nutrients for plant growth and crop yield. It is well documented that changes in nitrate availability, the main N source found in agricultural soils, influences a myriad of developmental programs and processes including the plant defense response. Indeed, many agronomical reports indicate that the plant N nutritional status influences their ability to respond effectively when challenged by different pathogens. However, the molecular mechanisms involved in N-modulation of plant susceptibility to pathogens are poorly characterized. In this work, we show that Solanum lycopersicum defense response to the necrotrophic fungus Botrytis cinerea is affected by plant N availability, with higher susceptibility in nitrate-limiting conditions. Global gene expression responses of tomato against B. cinerea under contrasting nitrate conditions reveals that plant primary metabolism is affected by the fungal infection regardless of N regimes. This result suggests that differential susceptibility to pathogen attack under contrasting N conditions is not only explained by a metabolic alteration. We used a systems biology approach to identify the transcriptional regulatory network implicated in plant response to the fungus infection under contrasting nitrate conditions. Interestingly, hub genes in this network are known key transcription factors involved in ethylene and jasmonic acid signaling. This result positions these hormones as key integrators of nitrate and defense against B. cinerea in tomato plants. Our results provide insights into potential crosstalk mechanisms between necrotrophic defense response and N status in plants.
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