ArticlePlant physiology2016
Genome-Wide Analysis of Alternative Splicing during Development and Drought Stress in Maize.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.
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Who cites it
126 citing papers in PubMed, 274 citations in OpenAlex.
- Splicing Factors in Plant Abiotic Stress Responses: Regulatory Mechanisms and Perspectives.Plants (Basel, Switzerland) · 2026Review
- Genetic coupling of leaf and kernel-related traits shapes drought adaptation in maize.The Plant journal : for cell and molecular biology · 2026Article
- Changes in the Proteome and Phosphoproteome ofProteomes · 2026Article
- Characterization of the BPC genes in alfalfa and functional verification of MsBPC10 in salt tolerance.BMC plant biology · 2026Article
- Genomic basis underlying alternative transcripts-mediated drought tolerance in maize.Genome biology · 2026Article
- Comprehensive analysis of alternative splicing and transcriptome diversity in apple using long-read sequencing.Frontiers in plant science · 2026Article
- Stress-responsive transcription factor families are key components of the core abiotic stress response in maize.G3 (Bethesda, Md.) · 2025Article
- Deciphering the ecodormancy and survival strategies of tropical water lily in northern subtropical environments.BMC plant biology · 2025Article
- Comprehensive analysis of dehydrin genes reveals ZmDHN3 contributes to drought resistance in maize (Zea Mays L.).BMC plant biology · 2025Article
- Genetic Dissection of Drought Tolerance in Maize Through GWAS of Agronomic Traits, Stress Tolerance Indices, and Phenotypic Plasticity.International journal of molecular sciences · 2025Article
- Identification ofPlants (Basel, Switzerland) · 2024Article
- A Genome-Wide Alternative Splicing Analysis ofPlants (Basel, Switzerland) · 2024Article
- Population-level exploration of alternative splicing and its unique role in controlling agronomic traits of rice.The Plant cell · 2024Article
- Alternative splicing dynamically regulates common carp embryogenesis under thermal stress.BMC genomics · 2024Article
- Integrative analyses of long and short-read RNA sequencing reveal the spliced isoform regulatory network of seedling growth dynamics in upland cotton.Functional & integrative genomics · 2024Article
- Alternative Splicing Underpins the ALMT9 Transporter Function for Vacuolar Malic Acid Accumulation in Apple.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Functional Validation of Different Alternative Splicing Variants of theCurrent issues in molecular biology · 2024Article
- Importance of pre-mRNA splicing and its study tools in plants.Advanced biotechnology · 2024Review
- The Emerging Role of Non-Coding RNAs (ncRNAs) in Plant Growth, Development, and Stress Response Signaling.Non-coding RNA · 2024Review
- Alternative splicing responses to salt stress inFrontiers in genetics · 2024Article
66 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alternative splicing plays a crucial role in plant development as well as stress responses. Although alternative splicing has been studied during development and in response to stress, the interplay between these two factors remains an open question. To assess the effects of drought stress on developmentally regulated splicing in maize (Zea mays), 94 RNA-seq libraries from ear, tassel, and leaf of the B73 public inbred line were constructed at four developmental stages under both well-watered and drought conditions. This analysis was supplemented with a publicly available series of 53 libraries from developing seed, embryo, and endosperm. More than 48,000 novel isoforms, often with stage- or condition-specific expression, were uncovered, suggesting that developmentally regulated alternative splicing occurs in thousands of genes. Drought induced large developmental splicing changes in leaf and ear but relatively few in tassel. Most developmental stage-specific splicing changes affected by drought were tissue dependent, whereas stage-independent changes frequently overlapped between leaf and ear. A linear relationship was found between gene expression changes in splicing factors and alternative spicing of other genes during development. Collectively, these results demonstrate that alternative splicing is strongly associated with tissue type, developmental stage, and stress condition.
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