Evidence map›Paper›PMID 26582308›Full record

ArticleVeterinary research2015

Protective effect of anti-SUAM antibodies on Streptococcus uberis mastitis.

Raúl A Almeida, Oudessa Kerro-Dego, María E Prado, Susan I Headrick, Mark J Lewis, Lydia J Siebert, Gina M Pighetti, Stephen P Oliver

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Effect ofAnimals : an open access journal from MDPI · 2021
    Article
  8. Review
  9. Evaluation ofVaccines · 2021
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Raúl A AlmeidaDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. ralmeida@utk.edu.
Oudessa Kerro-DegoDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. okerrode@utk.edu.
María E PradoDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. meprado@utk.edu.
Susan I HeadrickDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. ivey@utk.edu.
Mark J LewisLittle River Animal and Environmental Unit, East Tennessee AgResearch and Education Center, Walland, TN, 37886, USA. mlewis3@utk.edu.
Lydia J SiebertDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. lsiebert@utk.edu.
Gina M PighettiDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. pighetti@utk.edu.
Stephen P OliverDepartment of Animal Science, The University of Tennessee, Knoxville, TN, 37996-4574, USA. soliver@utk.edu.
University of Tennessee at Knoxville · USSoutheast Watershed Research Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, the effect of anti-recombinant Streptococcus uberis adhesion molecule (SUAM) antibodies against S. uberis intramammary infections (IMI) was evaluated using a passive protection model. Mammary quarters of healthy cows were infused with S. uberis UT888 opsonized with affinity purified anti-rSUAM antibodies or hyperimmune sera. Non-opsonized S. uberis UT888 were used as a control. Mammary quarters infused with opsonized S. uberis showed mild-to undetectable clinical symptoms of mastitis, lower milk bacterial counts, and less infected mammary quarters as compared to mammary quarters infused with non-opsonized S. uberis. These findings suggest that anti-rSUAM antibodies interfered with infection of mammary gland by S. uberis which might be through preventing adherence to and internalization into mammary gland cells, thus facilitating clearance of S. uberis, reducing colonization, and causing less IMI.

Indexed as

AnimalsAntibodies, BacterialAntigens, BacterialCattleFemaleMammary Glands, AnimalMastitis, BovineStreptococcal VaccinesStreptococcusVaccines, SyntheticAntibodies, BacterialAntigens, BacterialStreptococcal VaccinesVaccines, Synthetic

Identifiers

PMID26582308
PMCPMC4652381
OpenAlexW2177276657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.